Hemorrhage, Impaired Hematopoiesis, and Lethality in Mouse Embryos Carrying a Targeted Disruption of the Fli1 Transcription Factor super()

The Ets family of transcription factors have been suggested to function as key regulators of hematopoeisis. Here we describe aberrant hematopoeisis and hemorrhaging in mouse embryos homozygous for a targeted disruption in the Ets family member, Fli1. Mutant embryos are found to hemorrhage from the d...

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Veröffentlicht in:	Molecular and cellular biology 2000-08, Vol.20 (15), p.5643-5652
Hauptverfasser:	Spyropoulos, D D, Pharr, P N, Lavenburg, K R, Jackers, P, Papas, T S, Ogawa, M, Watson, D K
Format:	Artikel
Sprache:	eng
Schlagworte:	Fli1 gene
Online-Zugang:	Volltext
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