Bacterial Degradation of Microcystins and Nodularin

Microcystins and nodularins produced by cyanobacteria are potent hepatotoxins and tumor promoters. They are, respectively, cyclic heptapeptides and cyclic pentapeptides containing a characteristic β-amino acid residue, (2S,3S,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4(E ),6(E)-dienoic...

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Veröffentlicht in:	Chemical research in toxicology 2005-03, Vol.18 (3), p.591-598
Hauptverfasser:	Imanishi, Susumu, Kato, Hajime, Mizuno, Masayoshi, Tsuji, Kiyomi, Harada, Ken-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Toxins - metabolism Biodegradation, Environmental Chromatography, High Pressure Liquid Cyanobacteria - enzymology Enzyme Inhibitors - pharmacology Freshwater Microcystins Peptides, Cyclic - analysis Peptides, Cyclic - metabolism Spectrometry, Mass, Electrospray Ionization
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