Fc-Gamma Receptor Polymorphisms Predispose Patients to Infectious Complications After Liver Transplantation

We investigated the impact of polymorphisms in host innate immunoregulatory genes on the development of infectious complications after liver transplantation (LT). The single-nucleotide polymorphisms (SNPs) of C1QA [276A/G], FCGR2A [131H/R], and FCGR3A [158F/V], genes encoding the Fc gamma receptor (...

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Veröffentlicht in:	American journal of transplantation 2016-02, Vol.16 (2), p.625-633
Hauptverfasser:	Shimizu, S., Tanaka, Y., Tazawa, H., Verma, S., Onoe, T., Ishiyama, K., Ohira, M., Ide, K., Ohdan, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged clinical research/practice Communicable Diseases - diagnosis Communicable Diseases - drug therapy Communicable Diseases - etiology complication: infectious Cytomegalovirus Fc receptors Female Follow-Up Studies Gene polymorphism Genes genetics Graft Rejection - diagnosis Graft Rejection - drug therapy Graft Rejection - etiology Graft Survival Health risks Humans Immunoglobulin G Immunoregulation Immunosuppressive Agents - therapeutic use Infections infectious disease Liver Diseases - complications Liver Diseases - surgery Liver transplantation Liver Transplantation - adverse effects liver transplantation/hepatology liver transplantation: living donor Liver transplants Male Methicillin Middle Aged molecular biology: single polynucleotide polymorphism natural killer (NK) cells/NK receptors Polymorphism Polymorphism, Single Nucleotide - genetics Postoperative Complications Preoperative Care Prognosis Prospective Studies Receptors, IgG - genetics Risk Factors Single-nucleotide polymorphism Staphylococcus infections translational research/science Transplants & implants Young Adult
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