How to improve the prevention of chemotherapy-induced nausea and vomiting? The French NAVI study
Purpose Chemotherapy-induced nausea and vomiting (CINV) still remain frequent. The procedure for announcing the diagnosis (PAD) was an emblematic measure of the first French Plan Cancer aiming at providing patients with time to listen, information after cancer diagnosis, and discussion on treatments...
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Veröffentlicht in: | Supportive care in cancer 2016-03, Vol.24 (3), p.1131-1138 |
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creator | Vanbockstael, Julie Coquan, Elodie Gouerant, Sophie Allouache, Djelila Faveyrial, Audrey Noal, Sabine Delcambre, Corinne Galais, Marie-Pierre Héron, Jean-François Lefebvre, Anne-Charlotte Sevin, Emmanuel Hrab, Ioana Polycarpe, Florence André, Michel Kaluzinski, Laure Gervais, Radj Gunzer, Katharina Vié, Brigitte Saucier, Gilles Lemenand, Noëmie Grellard, Jean-Michel Clarisse, Bénédicte Dugué, Audrey Emmanuelle Joly, Florence |
description | Purpose
Chemotherapy-induced nausea and vomiting (CINV) still remain frequent. The procedure for announcing the diagnosis (PAD) was an emblematic measure of the first French Plan Cancer aiming at providing patients with time to listen, information after cancer diagnosis, and discussion on treatments and their side effects. We aimed at assessing the risk factors of CINV, focusing on patients’ satisfaction with the PAD.
Methods
This prospective multicentre study assessed the frequency and intensity of CINV among chemonaïve patients during the first cycle of treatment. CINV was defined by ≥1 emetic episode or reported nausea intensity ≥3 on a 0–10 scale. Multivariate analysis was used to identify factors related to global CINV onset including satisfaction with the PAD (satisfaction score ≥the median on a 0–10 scale).
Results
Data from 291 patients (women, 85.2 %; mean age, 57 years) were analyzed. Most patients (69.4 %) received highly emetogenic chemotherapy regimens and 77.7 % received antiemetic drugs consistent with international guidelines. Acute, delayed and overall CINV were experienced by 40.4, 34.8 and 52.4 % of patients, respectively. Sixty-seven per cent of patients were satisfied with the PAD. No relation was noted between PAD satisfaction and CINV onset. The nausea and vomiting dimension of the QLQ-C30 questionnaire before chemotherapy (OR 3.62), motion sickness history (OR 2.73), highly emetogenic CT (OR 2.73), anxiety (OR 1.99) and younger age (OR 1.96) were independent predictive factors.
Conclusions
Although patients were mostly satisfied with the PAD, half of them experienced CINV. A state of anxiety could be identified during the PAD to be managed. |
doi_str_mv | 10.1007/s00520-015-2882-7 |
format | Article |
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Chemotherapy-induced nausea and vomiting (CINV) still remain frequent. The procedure for announcing the diagnosis (PAD) was an emblematic measure of the first French Plan Cancer aiming at providing patients with time to listen, information after cancer diagnosis, and discussion on treatments and their side effects. We aimed at assessing the risk factors of CINV, focusing on patients’ satisfaction with the PAD.
Methods
This prospective multicentre study assessed the frequency and intensity of CINV among chemonaïve patients during the first cycle of treatment. CINV was defined by ≥1 emetic episode or reported nausea intensity ≥3 on a 0–10 scale. Multivariate analysis was used to identify factors related to global CINV onset including satisfaction with the PAD (satisfaction score ≥the median on a 0–10 scale).
Results
Data from 291 patients (women, 85.2 %; mean age, 57 years) were analyzed. Most patients (69.4 %) received highly emetogenic chemotherapy regimens and 77.7 % received antiemetic drugs consistent with international guidelines. Acute, delayed and overall CINV were experienced by 40.4, 34.8 and 52.4 % of patients, respectively. Sixty-seven per cent of patients were satisfied with the PAD. No relation was noted between PAD satisfaction and CINV onset. The nausea and vomiting dimension of the QLQ-C30 questionnaire before chemotherapy (OR 3.62), motion sickness history (OR 2.73), highly emetogenic CT (OR 2.73), anxiety (OR 1.99) and younger age (OR 1.96) were independent predictive factors.
Conclusions
Although patients were mostly satisfied with the PAD, half of them experienced CINV. A state of anxiety could be identified during the PAD to be managed.</description><identifier>ISSN: 0941-4355</identifier><identifier>EISSN: 1433-7339</identifier><identifier>DOI: 10.1007/s00520-015-2882-7</identifier><identifier>PMID: 26268784</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Analysis ; Antiemetics - therapeutic use ; Antineoplastic Agents - adverse effects ; Cancer ; Care and treatment ; Chemotherapy ; Female ; France ; Gastrointestinal agents ; Humans ; Male ; Medicine ; Medicine & Public Health ; Methods ; Middle Aged ; Nausea ; Nausea - chemically induced ; Nausea - prevention & control ; Neoplasms - complications ; Neoplasms - drug therapy ; Nursing ; Nursing Research ; Oncology ; Original Article ; Pain Medicine ; Prevention ; Prospective Studies ; Rehabilitation Medicine ; Studies ; Vomiting ; Vomiting - chemically induced ; Vomiting - prevention & control</subject><ispartof>Supportive care in cancer, 2016-03, Vol.24 (3), p.1131-1138</ispartof><rights>Springer-Verlag Berlin Heidelberg 2015</rights><rights>COPYRIGHT 2016 Springer</rights><rights>Springer-Verlag Berlin Heidelberg 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c575t-848c0f8094f433bb8575c893c426b4c46805f835c8a85260dfa988ca7cd988353</citedby><cites>FETCH-LOGICAL-c575t-848c0f8094f433bb8575c893c426b4c46805f835c8a85260dfa988ca7cd988353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00520-015-2882-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00520-015-2882-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26268784$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vanbockstael, Julie</creatorcontrib><creatorcontrib>Coquan, Elodie</creatorcontrib><creatorcontrib>Gouerant, Sophie</creatorcontrib><creatorcontrib>Allouache, Djelila</creatorcontrib><creatorcontrib>Faveyrial, Audrey</creatorcontrib><creatorcontrib>Noal, Sabine</creatorcontrib><creatorcontrib>Delcambre, Corinne</creatorcontrib><creatorcontrib>Galais, Marie-Pierre</creatorcontrib><creatorcontrib>Héron, Jean-François</creatorcontrib><creatorcontrib>Lefebvre, Anne-Charlotte</creatorcontrib><creatorcontrib>Sevin, Emmanuel</creatorcontrib><creatorcontrib>Hrab, Ioana</creatorcontrib><creatorcontrib>Polycarpe, Florence</creatorcontrib><creatorcontrib>André, Michel</creatorcontrib><creatorcontrib>Kaluzinski, Laure</creatorcontrib><creatorcontrib>Gervais, Radj</creatorcontrib><creatorcontrib>Gunzer, Katharina</creatorcontrib><creatorcontrib>Vié, Brigitte</creatorcontrib><creatorcontrib>Saucier, Gilles</creatorcontrib><creatorcontrib>Lemenand, Noëmie</creatorcontrib><creatorcontrib>Grellard, Jean-Michel</creatorcontrib><creatorcontrib>Clarisse, Bénédicte</creatorcontrib><creatorcontrib>Dugué, Audrey Emmanuelle</creatorcontrib><creatorcontrib>Joly, Florence</creatorcontrib><title>How to improve the prevention of chemotherapy-induced nausea and vomiting? The French NAVI study</title><title>Supportive care in cancer</title><addtitle>Support Care Cancer</addtitle><addtitle>Support Care Cancer</addtitle><description>Purpose
Chemotherapy-induced nausea and vomiting (CINV) still remain frequent. The procedure for announcing the diagnosis (PAD) was an emblematic measure of the first French Plan Cancer aiming at providing patients with time to listen, information after cancer diagnosis, and discussion on treatments and their side effects. We aimed at assessing the risk factors of CINV, focusing on patients’ satisfaction with the PAD.
Methods
This prospective multicentre study assessed the frequency and intensity of CINV among chemonaïve patients during the first cycle of treatment. CINV was defined by ≥1 emetic episode or reported nausea intensity ≥3 on a 0–10 scale. Multivariate analysis was used to identify factors related to global CINV onset including satisfaction with the PAD (satisfaction score ≥the median on a 0–10 scale).
Results
Data from 291 patients (women, 85.2 %; mean age, 57 years) were analyzed. Most patients (69.4 %) received highly emetogenic chemotherapy regimens and 77.7 % received antiemetic drugs consistent with international guidelines. Acute, delayed and overall CINV were experienced by 40.4, 34.8 and 52.4 % of patients, respectively. Sixty-seven per cent of patients were satisfied with the PAD. No relation was noted between PAD satisfaction and CINV onset. The nausea and vomiting dimension of the QLQ-C30 questionnaire before chemotherapy (OR 3.62), motion sickness history (OR 2.73), highly emetogenic CT (OR 2.73), anxiety (OR 1.99) and younger age (OR 1.96) were independent predictive factors.
Conclusions
Although patients were mostly satisfied with the PAD, half of them experienced CINV. A state of anxiety could be identified during the PAD to be managed.</description><subject>Analysis</subject><subject>Antiemetics - therapeutic use</subject><subject>Antineoplastic Agents - adverse effects</subject><subject>Cancer</subject><subject>Care and treatment</subject><subject>Chemotherapy</subject><subject>Female</subject><subject>France</subject><subject>Gastrointestinal agents</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Nausea</subject><subject>Nausea - chemically induced</subject><subject>Nausea - prevention & control</subject><subject>Neoplasms - complications</subject><subject>Neoplasms - drug therapy</subject><subject>Nursing</subject><subject>Nursing Research</subject><subject>Oncology</subject><subject>Original Article</subject><subject>Pain Medicine</subject><subject>Prevention</subject><subject>Prospective Studies</subject><subject>Rehabilitation Medicine</subject><subject>Studies</subject><subject>Vomiting</subject><subject>Vomiting - chemically induced</subject><subject>Vomiting - prevention & control</subject><issn>0941-4355</issn><issn>1433-7339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kUtvEzEUhS0EomnhB7BBltiwcfFz7FmhqKK0UgWbwtY4njuJq4wd7JlU-fd4lJaXQF5c6fg796GD0CtGzxml-l2hVHFKKFOEG8OJfoIWTApBtBDtU7SgrWRECqVO0Gkpd5QyrRV_jk54wxujjVygb1fpHo8Jh2GX0x7wuAG8y7CHOIYUceqx38CQqpzd7kBC7CYPHY5uKuCwix3epyGMIa7f49vqvcwQ_QZ_Wn69xmWcusML9Kx32wIvH-oZ-nL54fbiitx8_nh9sbwhXmk1EiONp72pG_f1gNXKVNWbVnjJm5X0sjFU9UZUzRnFG9r1rjXGO-27WoUSZ-jtsW-94_sEZbRDKB62WxchTcUy3TDZyFa0FX3zF3qXphzrdjNFNRdcsF_U2m3BhtinMTs_N7VLKblpKVfz2PN_UPV1MASfIvSh6n8Y2NHgcyolQ293OQwuHyyjdk7VHlO1NVU7p2p19bx-WHhaDdD9dDzGWAF-BEr9imvIv130364_AIghqY0</recordid><startdate>20160301</startdate><enddate>20160301</enddate><creator>Vanbockstael, Julie</creator><creator>Coquan, Elodie</creator><creator>Gouerant, Sophie</creator><creator>Allouache, Djelila</creator><creator>Faveyrial, Audrey</creator><creator>Noal, Sabine</creator><creator>Delcambre, Corinne</creator><creator>Galais, Marie-Pierre</creator><creator>Héron, Jean-François</creator><creator>Lefebvre, Anne-Charlotte</creator><creator>Sevin, Emmanuel</creator><creator>Hrab, Ioana</creator><creator>Polycarpe, Florence</creator><creator>André, Michel</creator><creator>Kaluzinski, Laure</creator><creator>Gervais, Radj</creator><creator>Gunzer, Katharina</creator><creator>Vié, Brigitte</creator><creator>Saucier, Gilles</creator><creator>Lemenand, Noëmie</creator><creator>Grellard, Jean-Michel</creator><creator>Clarisse, Bénédicte</creator><creator>Dugué, Audrey Emmanuelle</creator><creator>Joly, Florence</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2R</scope><scope>M2S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20160301</creationdate><title>How to improve the prevention of chemotherapy-induced nausea and vomiting? The French NAVI study</title><author>Vanbockstael, Julie ; Coquan, Elodie ; Gouerant, Sophie ; Allouache, Djelila ; Faveyrial, Audrey ; Noal, Sabine ; Delcambre, Corinne ; Galais, Marie-Pierre ; Héron, Jean-François ; Lefebvre, Anne-Charlotte ; Sevin, Emmanuel ; Hrab, Ioana ; Polycarpe, Florence ; André, Michel ; Kaluzinski, Laure ; Gervais, Radj ; Gunzer, Katharina ; Vié, Brigitte ; Saucier, Gilles ; Lemenand, Noëmie ; Grellard, Jean-Michel ; Clarisse, Bénédicte ; Dugué, Audrey Emmanuelle ; Joly, Florence</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c575t-848c0f8094f433bb8575c893c426b4c46805f835c8a85260dfa988ca7cd988353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Analysis</topic><topic>Antiemetics - therapeutic use</topic><topic>Antineoplastic Agents - adverse effects</topic><topic>Cancer</topic><topic>Care and treatment</topic><topic>Chemotherapy</topic><topic>Female</topic><topic>France</topic><topic>Gastrointestinal agents</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Methods</topic><topic>Middle Aged</topic><topic>Nausea</topic><topic>Nausea - chemically induced</topic><topic>Nausea - prevention & control</topic><topic>Neoplasms - complications</topic><topic>Neoplasms - drug therapy</topic><topic>Nursing</topic><topic>Nursing Research</topic><topic>Oncology</topic><topic>Original Article</topic><topic>Pain Medicine</topic><topic>Prevention</topic><topic>Prospective Studies</topic><topic>Rehabilitation Medicine</topic><topic>Studies</topic><topic>Vomiting</topic><topic>Vomiting - chemically induced</topic><topic>Vomiting - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vanbockstael, Julie</creatorcontrib><creatorcontrib>Coquan, Elodie</creatorcontrib><creatorcontrib>Gouerant, Sophie</creatorcontrib><creatorcontrib>Allouache, Djelila</creatorcontrib><creatorcontrib>Faveyrial, Audrey</creatorcontrib><creatorcontrib>Noal, Sabine</creatorcontrib><creatorcontrib>Delcambre, Corinne</creatorcontrib><creatorcontrib>Galais, Marie-Pierre</creatorcontrib><creatorcontrib>Héron, Jean-François</creatorcontrib><creatorcontrib>Lefebvre, Anne-Charlotte</creatorcontrib><creatorcontrib>Sevin, Emmanuel</creatorcontrib><creatorcontrib>Hrab, Ioana</creatorcontrib><creatorcontrib>Polycarpe, Florence</creatorcontrib><creatorcontrib>André, Michel</creatorcontrib><creatorcontrib>Kaluzinski, Laure</creatorcontrib><creatorcontrib>Gervais, Radj</creatorcontrib><creatorcontrib>Gunzer, Katharina</creatorcontrib><creatorcontrib>Vié, Brigitte</creatorcontrib><creatorcontrib>Saucier, Gilles</creatorcontrib><creatorcontrib>Lemenand, Noëmie</creatorcontrib><creatorcontrib>Grellard, Jean-Michel</creatorcontrib><creatorcontrib>Clarisse, Bénédicte</creatorcontrib><creatorcontrib>Dugué, Audrey Emmanuelle</creatorcontrib><creatorcontrib>Joly, Florence</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Sociology Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Social Science Database</collection><collection>Sociology Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Supportive care in cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vanbockstael, Julie</au><au>Coquan, Elodie</au><au>Gouerant, Sophie</au><au>Allouache, Djelila</au><au>Faveyrial, Audrey</au><au>Noal, Sabine</au><au>Delcambre, Corinne</au><au>Galais, Marie-Pierre</au><au>Héron, Jean-François</au><au>Lefebvre, Anne-Charlotte</au><au>Sevin, Emmanuel</au><au>Hrab, Ioana</au><au>Polycarpe, Florence</au><au>André, Michel</au><au>Kaluzinski, Laure</au><au>Gervais, Radj</au><au>Gunzer, Katharina</au><au>Vié, Brigitte</au><au>Saucier, Gilles</au><au>Lemenand, Noëmie</au><au>Grellard, Jean-Michel</au><au>Clarisse, Bénédicte</au><au>Dugué, Audrey Emmanuelle</au><au>Joly, Florence</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How to improve the prevention of chemotherapy-induced nausea and vomiting? The French NAVI study</atitle><jtitle>Supportive care in cancer</jtitle><stitle>Support Care Cancer</stitle><addtitle>Support Care Cancer</addtitle><date>2016-03-01</date><risdate>2016</risdate><volume>24</volume><issue>3</issue><spage>1131</spage><epage>1138</epage><pages>1131-1138</pages><issn>0941-4355</issn><eissn>1433-7339</eissn><abstract>Purpose
Chemotherapy-induced nausea and vomiting (CINV) still remain frequent. The procedure for announcing the diagnosis (PAD) was an emblematic measure of the first French Plan Cancer aiming at providing patients with time to listen, information after cancer diagnosis, and discussion on treatments and their side effects. We aimed at assessing the risk factors of CINV, focusing on patients’ satisfaction with the PAD.
Methods
This prospective multicentre study assessed the frequency and intensity of CINV among chemonaïve patients during the first cycle of treatment. CINV was defined by ≥1 emetic episode or reported nausea intensity ≥3 on a 0–10 scale. Multivariate analysis was used to identify factors related to global CINV onset including satisfaction with the PAD (satisfaction score ≥the median on a 0–10 scale).
Results
Data from 291 patients (women, 85.2 %; mean age, 57 years) were analyzed. Most patients (69.4 %) received highly emetogenic chemotherapy regimens and 77.7 % received antiemetic drugs consistent with international guidelines. Acute, delayed and overall CINV were experienced by 40.4, 34.8 and 52.4 % of patients, respectively. Sixty-seven per cent of patients were satisfied with the PAD. No relation was noted between PAD satisfaction and CINV onset. The nausea and vomiting dimension of the QLQ-C30 questionnaire before chemotherapy (OR 3.62), motion sickness history (OR 2.73), highly emetogenic CT (OR 2.73), anxiety (OR 1.99) and younger age (OR 1.96) were independent predictive factors.
Conclusions
Although patients were mostly satisfied with the PAD, half of them experienced CINV. A state of anxiety could be identified during the PAD to be managed.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>26268784</pmid><doi>10.1007/s00520-015-2882-7</doi><tpages>8</tpages></addata></record> |
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ispartof | Supportive care in cancer, 2016-03, Vol.24 (3), p.1131-1138 |
issn | 0941-4355 1433-7339 |
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source | MEDLINE; SpringerLink Journals - AutoHoldings |
subjects | Analysis Antiemetics - therapeutic use Antineoplastic Agents - adverse effects Cancer Care and treatment Chemotherapy Female France Gastrointestinal agents Humans Male Medicine Medicine & Public Health Methods Middle Aged Nausea Nausea - chemically induced Nausea - prevention & control Neoplasms - complications Neoplasms - drug therapy Nursing Nursing Research Oncology Original Article Pain Medicine Prevention Prospective Studies Rehabilitation Medicine Studies Vomiting Vomiting - chemically induced Vomiting - prevention & control |
title | How to improve the prevention of chemotherapy-induced nausea and vomiting? The French NAVI study |
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