Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol

Ethanol shares with all major dependence producing drugs the ability to activate brain mesocorticolimbic dopamine neurons, an important part of the brain reward systems. This dopamine activation may be involved in mediating the positive reinforcing effects of ethanol. The mechanisms of action of eth...

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Veröffentlicht in:	Behavioural brain research 2000-08, Vol.113 (1), p.85-96
Hauptverfasser:	Söderpalm, Bo, Ericson, Mia, Olausson, Peter, Blomqvist, Ola, Engel, Jörgen A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking - physiopathology Animals Behavioral psychophysiology Biological and medical sciences Brain - physiopathology Brain Mapping Chronic Disinhibition Dopamine - physiology Ethanol Fundamental and applied biological sciences. Psychology Humans Mesolimbic dopamine Mice Microdialysis Motivation Neurotransmission and behavior Nicotinic acetylcholine receptor Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rat Rats Receptors, Nicotinic - physiology Reinforcement Tobacco Use Disorder - physiopathology ventral tegmental area
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