A shift in priority in diabetic foot care and research: 75% of foot ulcers are preventable
Diabetic foot ulceration poses a heavy burden on the patient and the healthcare system, but prevention thereof receives little attention. For every euro spent on ulcer prevention, ten are spent on ulcer healing, and for every randomized controlled trial conducted on prevention, ten are conducted on...
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Veröffentlicht in: | Diabetes/metabolism research and reviews 2016-01, Vol.32 (S1), p.195-200 |
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description | Diabetic foot ulceration poses a heavy burden on the patient and the healthcare system, but prevention thereof receives little attention. For every euro spent on ulcer prevention, ten are spent on ulcer healing, and for every randomized controlled trial conducted on prevention, ten are conducted on healing. In this article, we argue that a shift in priorities is needed. For the prevention of a first foot ulcer, we need more insight into the effect of interventions and practices already applied globally in many settings. This requires systematic recording of interventions and outcomes, and well‐designed randomized controlled trials that include analysis of cost‐effectiveness. After healing of a foot ulcer, the risk of recurrence is high. For the prevention of a recurrent foot ulcer, home monitoring of foot temperature, pressure‐relieving therapeutic footwear, and certain surgical interventions prove to be effective. The median effect size found in a total of 23 studies on these interventions is large, over 60%, and further increases when patients are adherent to treatment. These interventions should be investigated for efficacy as a state‐of‐the‐art integrated foot care approach, where attempts are made to assure treatment adherence. Effect sizes of 75–80% may be expected. If such state‐of‐the‐art integrated foot care is implemented, the majority of problems with foot ulcer recurrence in diabetes can be resolved. It is therefore time to act and to set a new target in diabetic foot care. This target is to reduce foot ulcer incidence with at least 75%. Copyright © 2016 John Wiley & Sons, Ltd. |
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For every euro spent on ulcer prevention, ten are spent on ulcer healing, and for every randomized controlled trial conducted on prevention, ten are conducted on healing. In this article, we argue that a shift in priorities is needed. For the prevention of a first foot ulcer, we need more insight into the effect of interventions and practices already applied globally in many settings. This requires systematic recording of interventions and outcomes, and well‐designed randomized controlled trials that include analysis of cost‐effectiveness. After healing of a foot ulcer, the risk of recurrence is high. For the prevention of a recurrent foot ulcer, home monitoring of foot temperature, pressure‐relieving therapeutic footwear, and certain surgical interventions prove to be effective. The median effect size found in a total of 23 studies on these interventions is large, over 60%, and further increases when patients are adherent to treatment. These interventions should be investigated for efficacy as a state‐of‐the‐art integrated foot care approach, where attempts are made to assure treatment adherence. Effect sizes of 75–80% may be expected. If such state‐of‐the‐art integrated foot care is implemented, the majority of problems with foot ulcer recurrence in diabetes can be resolved. It is therefore time to act and to set a new target in diabetic foot care. This target is to reduce foot ulcer incidence with at least 75%. Copyright © 2016 John Wiley & Sons, Ltd.</description><identifier>ISSN: 1520-7552</identifier><identifier>EISSN: 1520-7560</identifier><identifier>DOI: 10.1002/dmrr.2738</identifier><identifier>PMID: 26452160</identifier><identifier>CODEN: DMRRFM</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>adherence ; classification ; Clinical trials ; Combined Modality Therapy - economics ; Congresses as Topic ; Cost Savings ; costs ; Diabetes ; Diabetes mellitus ; Diabetic Foot - economics ; Diabetic Foot - epidemiology ; Diabetic Foot - prevention & control ; Diabetic Foot - therapy ; Disease prevention ; Evidence-Based Medicine ; Feet ; Foot diseases ; foot ulcer ; Global Health ; Health Care Costs ; Health Priorities - trends ; Humans ; Leg ulcers ; Medical research ; Patient Compliance ; Patient Education as Topic - economics ; Patients ; Practice Guidelines as Topic ; Precision Medicine ; prevention ; Recurrence ; Risk Factors ; Self Care - economics ; Self Care - trends ; Shoes - adverse effects ; Shoes - economics ; Ulcers</subject><ispartof>Diabetes/metabolism research and reviews, 2016-01, Vol.32 (S1), p.195-200</ispartof><rights>Copyright © 2016 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5208-829176e793f1d81dfcd9092c762f2628365998466aa472375265bc060350628e3</citedby><cites>FETCH-LOGICAL-c5208-829176e793f1d81dfcd9092c762f2628365998466aa472375265bc060350628e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fdmrr.2738$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fdmrr.2738$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26452160$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bus, Sicco A.</creatorcontrib><creatorcontrib>van Netten, Jaap J.</creatorcontrib><title>A shift in priority in diabetic foot care and research: 75% of foot ulcers are preventable</title><title>Diabetes/metabolism research and reviews</title><addtitle>Diabetes Metab Res Rev</addtitle><description>Diabetic foot ulceration poses a heavy burden on the patient and the healthcare system, but prevention thereof receives little attention. For every euro spent on ulcer prevention, ten are spent on ulcer healing, and for every randomized controlled trial conducted on prevention, ten are conducted on healing. In this article, we argue that a shift in priorities is needed. For the prevention of a first foot ulcer, we need more insight into the effect of interventions and practices already applied globally in many settings. This requires systematic recording of interventions and outcomes, and well‐designed randomized controlled trials that include analysis of cost‐effectiveness. After healing of a foot ulcer, the risk of recurrence is high. For the prevention of a recurrent foot ulcer, home monitoring of foot temperature, pressure‐relieving therapeutic footwear, and certain surgical interventions prove to be effective. The median effect size found in a total of 23 studies on these interventions is large, over 60%, and further increases when patients are adherent to treatment. These interventions should be investigated for efficacy as a state‐of‐the‐art integrated foot care approach, where attempts are made to assure treatment adherence. Effect sizes of 75–80% may be expected. If such state‐of‐the‐art integrated foot care is implemented, the majority of problems with foot ulcer recurrence in diabetes can be resolved. It is therefore time to act and to set a new target in diabetic foot care. This target is to reduce foot ulcer incidence with at least 75%. Copyright © 2016 John Wiley & Sons, Ltd.</description><subject>adherence</subject><subject>classification</subject><subject>Clinical trials</subject><subject>Combined Modality Therapy - economics</subject><subject>Congresses as Topic</subject><subject>Cost Savings</subject><subject>costs</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetic Foot - economics</subject><subject>Diabetic Foot - epidemiology</subject><subject>Diabetic Foot - prevention & control</subject><subject>Diabetic Foot - therapy</subject><subject>Disease prevention</subject><subject>Evidence-Based Medicine</subject><subject>Feet</subject><subject>Foot diseases</subject><subject>foot ulcer</subject><subject>Global Health</subject><subject>Health Care Costs</subject><subject>Health Priorities - trends</subject><subject>Humans</subject><subject>Leg ulcers</subject><subject>Medical research</subject><subject>Patient Compliance</subject><subject>Patient Education as Topic - economics</subject><subject>Patients</subject><subject>Practice Guidelines as Topic</subject><subject>Precision Medicine</subject><subject>prevention</subject><subject>Recurrence</subject><subject>Risk Factors</subject><subject>Self Care - economics</subject><subject>Self Care - trends</subject><subject>Shoes - adverse effects</subject><subject>Shoes - economics</subject><subject>Ulcers</subject><issn>1520-7552</issn><issn>1520-7560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1v1DAQhi1ERT_gwB9AlhASHNKO7fgj3KoW2kpbPioQEhfL60xUl2yy2Elh_z2Ost0DEpxmpHnm0WheQp4zOGYA_KRexXjMtTCPyAGTHAotFTze9ZLvk8OU7gBAlKp8Qva5KiVnCg7I91OabkMz0NDRdQx9DMNm6uvgljgET5u-H6h3EanrahoxoYv-9i3V8hXtm3k8th5johO0jniP3eCWLT4le41rEz7b1iPy9f27L2eXxeLjxdXZ6aLw-TxTGF4xrVBXomG1YXXj6woq7rXiDVfcCCWrypRKOVdqLrTkSi49KBAS8hjFEXk9e9ex_zliGuwqJI9t6zrsx2SznYFhwlQZffkXetePscvXWQ5lFldGlP-jsguYLkGwTL2ZKR_7lCI2Nv9v5eLGMrBTLHaKxU6xZPbF1jguV1jvyIccMnAyA79Ci5t_m-z59c3NVlnMGyEN-Hu34eIPq3T-kv324cIuziuhP-nP9lL8AWTqoYg</recordid><startdate>201601</startdate><enddate>201601</enddate><creator>Bus, Sicco A.</creator><creator>van Netten, Jaap J.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201601</creationdate><title>A shift in priority in diabetic foot care and research: 75% of foot ulcers are preventable</title><author>Bus, Sicco A. ; van Netten, Jaap J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5208-829176e793f1d81dfcd9092c762f2628365998466aa472375265bc060350628e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>adherence</topic><topic>classification</topic><topic>Clinical trials</topic><topic>Combined Modality Therapy - economics</topic><topic>Congresses as Topic</topic><topic>Cost Savings</topic><topic>costs</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetic Foot - economics</topic><topic>Diabetic Foot - epidemiology</topic><topic>Diabetic Foot - prevention & control</topic><topic>Diabetic Foot - therapy</topic><topic>Disease prevention</topic><topic>Evidence-Based Medicine</topic><topic>Feet</topic><topic>Foot diseases</topic><topic>foot ulcer</topic><topic>Global Health</topic><topic>Health Care Costs</topic><topic>Health Priorities - trends</topic><topic>Humans</topic><topic>Leg ulcers</topic><topic>Medical research</topic><topic>Patient Compliance</topic><topic>Patient Education as Topic - economics</topic><topic>Patients</topic><topic>Practice Guidelines as Topic</topic><topic>Precision Medicine</topic><topic>prevention</topic><topic>Recurrence</topic><topic>Risk Factors</topic><topic>Self Care - economics</topic><topic>Self Care - trends</topic><topic>Shoes - adverse effects</topic><topic>Shoes - economics</topic><topic>Ulcers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bus, Sicco A.</creatorcontrib><creatorcontrib>van Netten, Jaap J.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Diabetes/metabolism research and reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bus, Sicco A.</au><au>van Netten, Jaap J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A shift in priority in diabetic foot care and research: 75% of foot ulcers are preventable</atitle><jtitle>Diabetes/metabolism research and reviews</jtitle><addtitle>Diabetes Metab Res Rev</addtitle><date>2016-01</date><risdate>2016</risdate><volume>32</volume><issue>S1</issue><spage>195</spage><epage>200</epage><pages>195-200</pages><issn>1520-7552</issn><eissn>1520-7560</eissn><coden>DMRRFM</coden><abstract>Diabetic foot ulceration poses a heavy burden on the patient and the healthcare system, but prevention thereof receives little attention. For every euro spent on ulcer prevention, ten are spent on ulcer healing, and for every randomized controlled trial conducted on prevention, ten are conducted on healing. In this article, we argue that a shift in priorities is needed. For the prevention of a first foot ulcer, we need more insight into the effect of interventions and practices already applied globally in many settings. This requires systematic recording of interventions and outcomes, and well‐designed randomized controlled trials that include analysis of cost‐effectiveness. After healing of a foot ulcer, the risk of recurrence is high. For the prevention of a recurrent foot ulcer, home monitoring of foot temperature, pressure‐relieving therapeutic footwear, and certain surgical interventions prove to be effective. The median effect size found in a total of 23 studies on these interventions is large, over 60%, and further increases when patients are adherent to treatment. These interventions should be investigated for efficacy as a state‐of‐the‐art integrated foot care approach, where attempts are made to assure treatment adherence. Effect sizes of 75–80% may be expected. If such state‐of‐the‐art integrated foot care is implemented, the majority of problems with foot ulcer recurrence in diabetes can be resolved. It is therefore time to act and to set a new target in diabetic foot care. This target is to reduce foot ulcer incidence with at least 75%. Copyright © 2016 John Wiley & Sons, Ltd.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>26452160</pmid><doi>10.1002/dmrr.2738</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | adherence classification Clinical trials Combined Modality Therapy - economics Congresses as Topic Cost Savings costs Diabetes Diabetes mellitus Diabetic Foot - economics Diabetic Foot - epidemiology Diabetic Foot - prevention & control Diabetic Foot - therapy Disease prevention Evidence-Based Medicine Feet Foot diseases foot ulcer Global Health Health Care Costs Health Priorities - trends Humans Leg ulcers Medical research Patient Compliance Patient Education as Topic - economics Patients Practice Guidelines as Topic Precision Medicine prevention Recurrence Risk Factors Self Care - economics Self Care - trends Shoes - adverse effects Shoes - economics Ulcers |
title | A shift in priority in diabetic foot care and research: 75% of foot ulcers are preventable |
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