Analysis and comparison of statin prescription patterns and outcomes according to clinical department
Summary What is known and objective There is a disparity between the Korean treatment guidelines and actual clinical prescription habits. This study was designed to evaluate the department‐specific disparities and achievement rates for low‐density lipoprotein cholesterol (LDL‐C) targets, based on ea...
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| Veröffentlicht in: | Journal of clinical pharmacy and therapeutics 2016-02, Vol.41 (1), p.70-77 |
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| container_title | Journal of clinical pharmacy and therapeutics |
| container_volume | 41 |
| creator | Kim, H.-S. Kim, H. Lee, H. Park, B. Park, S. Lee, S.-H. Cho, J. H. Song, H. Kim, J. H. Yoon, K.-H. Choi, I. Y. |
| description | Summary
What is known and objective
There is a disparity between the Korean treatment guidelines and actual clinical prescription habits. This study was designed to evaluate the department‐specific disparities and achievement rates for low‐density lipoprotein cholesterol (LDL‐C) targets, based on each department's specific statin prescription patterns.
Methods
We retrospectively evaluated data from 31 718 patients who had been prescribed a statin at least once between January 2008 and June 2013 at our institution. Patients were classified into the high‐risk (target LDL‐C |
| doi_str_mv | 10.1111/jcpt.12350 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1761076882</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3933539631</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4310-2a2d2d696406d12fa6884dda5378c77899d0dd1a4449de248f711b1ae35b780e3</originalsourceid><addsrcrecordid>eNp9kMtu1DAYRi1URKeFDQ9QRWKDKqX4ktjJsprSAVQui0FIbCyP_afykNip7ajM2-OZtF2wqDeWrfOdxUHoLcEXJJ8PWz2mC0JZjV-gBWG8Lqkg-AgtMOVtWQkqjtFJjFuMMReUvULHlIuWtLxZILh0qt9FGwvlTKH9MKpgo3eF74qYVLKuGANEHeyYbP4eVUoQ3Iz7KeUF5IfWPhjrbovkC91bZ7XqCwNZlgZw6TV62ak-wpuH-xT9vP64Xn4qb76vPi8vb0pdMYJLqqihhre8wtwQ2ineNJUxqmai0UI0bWuwMURVVdUaoFXTCUI2RAGrN6LBwE7R-9k7Bn83QUxysFFD3ysHfoqSCE6wyFaa0Xf_oVs_hRzjQGHKGiFYps5nSgcfY4BOjsEOKuwkwXIfX-7jy0P8DJ89KKfNAOYJfaydATID97aH3TMq-WX5Y_0oLeeNjQn-Pm1U-CO5YKKWv76t5NffV4wu-Vqu2T8Oe57d</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1760238773</pqid></control><display><type>article</type><title>Analysis and comparison of statin prescription patterns and outcomes according to clinical department</title><source>MEDLINE</source><source>Wiley Journals</source><creator>Kim, H.-S. ; Kim, H. ; Lee, H. ; Park, B. ; Park, S. ; Lee, S.-H. ; Cho, J. H. ; Song, H. ; Kim, J. H. ; Yoon, K.-H. ; Choi, I. Y.</creator><creatorcontrib>Kim, H.-S. ; Kim, H. ; Lee, H. ; Park, B. ; Park, S. ; Lee, S.-H. ; Cho, J. H. ; Song, H. ; Kim, J. H. ; Yoon, K.-H. ; Choi, I. Y.</creatorcontrib><description>Summary
What is known and objective
There is a disparity between the Korean treatment guidelines and actual clinical prescription habits. This study was designed to evaluate the department‐specific disparities and achievement rates for low‐density lipoprotein cholesterol (LDL‐C) targets, based on each department's specific statin prescription patterns.
Methods
We retrospectively evaluated data from 31 718 patients who had been prescribed a statin at least once between January 2008 and June 2013 at our institution. Patients were classified into the high‐risk (target LDL‐C < 100 mg/dL) or moderate‐risk (target LDL‐C < 130 mg/dL) groups, according to the National Cholesterol Education Programme‐Adult Treatment Panel III guidelines.
Results and discussion
Statins were most commonly prescribed in the cardiology (32·0%) and endocrinology (26·6%) departments. For the high‐risk group, 70% of patients in the cardiology, endocrinology and cardiac surgery departments achieved their target LDL‐C levels (<100 mg/dL). However, the target achievement rates in most other departments were <70%. For the moderate‐risk group, 79·2% of patients achieved their target levels. Departments that prescribed a greater number of high‐ or intermediate‐potency statins were more likely to achieve their target LDL‐C levels. The group that achieved their target LDL‐C levels (<100 mg/dL) exhibited a significant positive relationship (Spearman's correlation coefficient = 0·8571, P = 0·0065), from low to high potency.
What is new and conclusion
Some departments tend to undertreat when prescribing statins. However, to reach to the target LDL‐C levels, physicians must overcome their tendency to undertreat with statins. We believe that the target achievement rate will increase if doctors are more actively aware of a patient's individual status and related risk factors before prescribing statins.
Some departments tend to undertreat when prescribing statins. To reach to the target LDL‐C levels, physicians must overcome their tendency to undertreat with statins.</description><identifier>ISSN: 0269-4727</identifier><identifier>EISSN: 1365-2710</identifier><identifier>DOI: 10.1111/jcpt.12350</identifier><identifier>PMID: 26791968</identifier><identifier>CODEN: JCPTED</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Cholesterol, LDL - blood ; Female ; HMG-CoA reductase inhibitor (statin) ; Hospital Departments - statistics & numerical data ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use ; Hypercholesterolaemia ; LDL-cholesterol ; Male ; Middle Aged ; Practice Guidelines as Topic ; Practice Patterns, Physicians' - standards ; Practice Patterns, Physicians' - statistics & numerical data ; Republic of Korea ; Retrospective Studies ; Risk Factors ; target achievement rate ; treatment gap ; Young Adult</subject><ispartof>Journal of clinical pharmacy and therapeutics, 2016-02, Vol.41 (1), p.70-77</ispartof><rights>2016 John Wiley & Sons Ltd</rights><rights>2016 John Wiley & Sons Ltd.</rights><rights>Copyright © 2016 John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4310-2a2d2d696406d12fa6884dda5378c77899d0dd1a4449de248f711b1ae35b780e3</citedby><cites>FETCH-LOGICAL-c4310-2a2d2d696406d12fa6884dda5378c77899d0dd1a4449de248f711b1ae35b780e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjcpt.12350$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjcpt.12350$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26791968$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, H.-S.</creatorcontrib><creatorcontrib>Kim, H.</creatorcontrib><creatorcontrib>Lee, H.</creatorcontrib><creatorcontrib>Park, B.</creatorcontrib><creatorcontrib>Park, S.</creatorcontrib><creatorcontrib>Lee, S.-H.</creatorcontrib><creatorcontrib>Cho, J. H.</creatorcontrib><creatorcontrib>Song, H.</creatorcontrib><creatorcontrib>Kim, J. H.</creatorcontrib><creatorcontrib>Yoon, K.-H.</creatorcontrib><creatorcontrib>Choi, I. Y.</creatorcontrib><title>Analysis and comparison of statin prescription patterns and outcomes according to clinical department</title><title>Journal of clinical pharmacy and therapeutics</title><addtitle>J Clin Pharm Ther</addtitle><description>Summary
What is known and objective
There is a disparity between the Korean treatment guidelines and actual clinical prescription habits. This study was designed to evaluate the department‐specific disparities and achievement rates for low‐density lipoprotein cholesterol (LDL‐C) targets, based on each department's specific statin prescription patterns.
Methods
We retrospectively evaluated data from 31 718 patients who had been prescribed a statin at least once between January 2008 and June 2013 at our institution. Patients were classified into the high‐risk (target LDL‐C < 100 mg/dL) or moderate‐risk (target LDL‐C < 130 mg/dL) groups, according to the National Cholesterol Education Programme‐Adult Treatment Panel III guidelines.
Results and discussion
Statins were most commonly prescribed in the cardiology (32·0%) and endocrinology (26·6%) departments. For the high‐risk group, 70% of patients in the cardiology, endocrinology and cardiac surgery departments achieved their target LDL‐C levels (<100 mg/dL). However, the target achievement rates in most other departments were <70%. For the moderate‐risk group, 79·2% of patients achieved their target levels. Departments that prescribed a greater number of high‐ or intermediate‐potency statins were more likely to achieve their target LDL‐C levels. The group that achieved their target LDL‐C levels (<100 mg/dL) exhibited a significant positive relationship (Spearman's correlation coefficient = 0·8571, P = 0·0065), from low to high potency.
What is new and conclusion
Some departments tend to undertreat when prescribing statins. However, to reach to the target LDL‐C levels, physicians must overcome their tendency to undertreat with statins. We believe that the target achievement rate will increase if doctors are more actively aware of a patient's individual status and related risk factors before prescribing statins.
Some departments tend to undertreat when prescribing statins. To reach to the target LDL‐C levels, physicians must overcome their tendency to undertreat with statins.</description><subject>Adult</subject><subject>Aged</subject><subject>Cholesterol, LDL - blood</subject><subject>Female</subject><subject>HMG-CoA reductase inhibitor (statin)</subject><subject>Hospital Departments - statistics & numerical data</subject><subject>Humans</subject><subject>Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage</subject><subject>Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use</subject><subject>Hypercholesterolaemia</subject><subject>LDL-cholesterol</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Practice Guidelines as Topic</subject><subject>Practice Patterns, Physicians' - standards</subject><subject>Practice Patterns, Physicians' - statistics & numerical data</subject><subject>Republic of Korea</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>target achievement rate</subject><subject>treatment gap</subject><subject>Young Adult</subject><issn>0269-4727</issn><issn>1365-2710</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtu1DAYRi1URKeFDQ9QRWKDKqX4ktjJsprSAVQui0FIbCyP_afykNip7ajM2-OZtF2wqDeWrfOdxUHoLcEXJJ8PWz2mC0JZjV-gBWG8Lqkg-AgtMOVtWQkqjtFJjFuMMReUvULHlIuWtLxZILh0qt9FGwvlTKH9MKpgo3eF74qYVLKuGANEHeyYbP4eVUoQ3Iz7KeUF5IfWPhjrbovkC91bZ7XqCwNZlgZw6TV62ak-wpuH-xT9vP64Xn4qb76vPi8vb0pdMYJLqqihhre8wtwQ2ineNJUxqmai0UI0bWuwMURVVdUaoFXTCUI2RAGrN6LBwE7R-9k7Bn83QUxysFFD3ysHfoqSCE6wyFaa0Xf_oVs_hRzjQGHKGiFYps5nSgcfY4BOjsEOKuwkwXIfX-7jy0P8DJ89KKfNAOYJfaydATID97aH3TMq-WX5Y_0oLeeNjQn-Pm1U-CO5YKKWv76t5NffV4wu-Vqu2T8Oe57d</recordid><startdate>201602</startdate><enddate>201602</enddate><creator>Kim, H.-S.</creator><creator>Kim, H.</creator><creator>Lee, H.</creator><creator>Park, B.</creator><creator>Park, S.</creator><creator>Lee, S.-H.</creator><creator>Cho, J. H.</creator><creator>Song, H.</creator><creator>Kim, J. H.</creator><creator>Yoon, K.-H.</creator><creator>Choi, I. Y.</creator><general>Blackwell Publishing Ltd</general><general>Hindawi Limited</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TM</scope><scope>7TO</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>201602</creationdate><title>Analysis and comparison of statin prescription patterns and outcomes according to clinical department</title><author>Kim, H.-S. ; Kim, H. ; Lee, H. ; Park, B. ; Park, S. ; Lee, S.-H. ; Cho, J. H. ; Song, H. ; Kim, J. H. ; Yoon, K.-H. ; Choi, I. Y.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4310-2a2d2d696406d12fa6884dda5378c77899d0dd1a4449de248f711b1ae35b780e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Cholesterol, LDL - blood</topic><topic>Female</topic><topic>HMG-CoA reductase inhibitor (statin)</topic><topic>Hospital Departments - statistics & numerical data</topic><topic>Humans</topic><topic>Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage</topic><topic>Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use</topic><topic>Hypercholesterolaemia</topic><topic>LDL-cholesterol</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Practice Guidelines as Topic</topic><topic>Practice Patterns, Physicians' - standards</topic><topic>Practice Patterns, Physicians' - statistics & numerical data</topic><topic>Republic of Korea</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>target achievement rate</topic><topic>treatment gap</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, H.-S.</creatorcontrib><creatorcontrib>Kim, H.</creatorcontrib><creatorcontrib>Lee, H.</creatorcontrib><creatorcontrib>Park, B.</creatorcontrib><creatorcontrib>Park, S.</creatorcontrib><creatorcontrib>Lee, S.-H.</creatorcontrib><creatorcontrib>Cho, J. H.</creatorcontrib><creatorcontrib>Song, H.</creatorcontrib><creatorcontrib>Kim, J. H.</creatorcontrib><creatorcontrib>Yoon, K.-H.</creatorcontrib><creatorcontrib>Choi, I. Y.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical pharmacy and therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, H.-S.</au><au>Kim, H.</au><au>Lee, H.</au><au>Park, B.</au><au>Park, S.</au><au>Lee, S.-H.</au><au>Cho, J. H.</au><au>Song, H.</au><au>Kim, J. H.</au><au>Yoon, K.-H.</au><au>Choi, I. Y.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analysis and comparison of statin prescription patterns and outcomes according to clinical department</atitle><jtitle>Journal of clinical pharmacy and therapeutics</jtitle><addtitle>J Clin Pharm Ther</addtitle><date>2016-02</date><risdate>2016</risdate><volume>41</volume><issue>1</issue><spage>70</spage><epage>77</epage><pages>70-77</pages><issn>0269-4727</issn><eissn>1365-2710</eissn><coden>JCPTED</coden><abstract>Summary
What is known and objective
There is a disparity between the Korean treatment guidelines and actual clinical prescription habits. This study was designed to evaluate the department‐specific disparities and achievement rates for low‐density lipoprotein cholesterol (LDL‐C) targets, based on each department's specific statin prescription patterns.
Methods
We retrospectively evaluated data from 31 718 patients who had been prescribed a statin at least once between January 2008 and June 2013 at our institution. Patients were classified into the high‐risk (target LDL‐C < 100 mg/dL) or moderate‐risk (target LDL‐C < 130 mg/dL) groups, according to the National Cholesterol Education Programme‐Adult Treatment Panel III guidelines.
Results and discussion
Statins were most commonly prescribed in the cardiology (32·0%) and endocrinology (26·6%) departments. For the high‐risk group, 70% of patients in the cardiology, endocrinology and cardiac surgery departments achieved their target LDL‐C levels (<100 mg/dL). However, the target achievement rates in most other departments were <70%. For the moderate‐risk group, 79·2% of patients achieved their target levels. Departments that prescribed a greater number of high‐ or intermediate‐potency statins were more likely to achieve their target LDL‐C levels. The group that achieved their target LDL‐C levels (<100 mg/dL) exhibited a significant positive relationship (Spearman's correlation coefficient = 0·8571, P = 0·0065), from low to high potency.
What is new and conclusion
Some departments tend to undertreat when prescribing statins. However, to reach to the target LDL‐C levels, physicians must overcome their tendency to undertreat with statins. We believe that the target achievement rate will increase if doctors are more actively aware of a patient's individual status and related risk factors before prescribing statins.
Some departments tend to undertreat when prescribing statins. To reach to the target LDL‐C levels, physicians must overcome their tendency to undertreat with statins.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>26791968</pmid><doi>10.1111/jcpt.12350</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of clinical pharmacy and therapeutics, 2016-02, Vol.41 (1), p.70-77 |
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| subjects | Adult Aged Cholesterol, LDL - blood Female HMG-CoA reductase inhibitor (statin) Hospital Departments - statistics & numerical data Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hypercholesterolaemia LDL-cholesterol Male Middle Aged Practice Guidelines as Topic Practice Patterns, Physicians' - standards Practice Patterns, Physicians' - statistics & numerical data Republic of Korea Retrospective Studies Risk Factors target achievement rate treatment gap Young Adult |
| title | Analysis and comparison of statin prescription patterns and outcomes according to clinical department |
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