Clinical Trial Risk in Chronic Obstructive Pulmonary Disease: The Effects of Drug Class and Inclusion Criteria

Background: This study analyzed the risk of clinical trial failure in chronic obstructive pulmonary disease (COPD) drug development between 1998 and 2015. We investigated elements that influenced clinical trial risk and factors that could improve outcomes during development. Objectives: This study a...

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Veröffentlicht in:	Respiration 2016-01, Vol.91 (1), p.79-86
Hauptverfasser:	Tam, Jeffrey T.Y., Parker, Jayson L., Anastasopulos, Demetri, Balter, Meyer S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Adrenal Cortex Hormones - therapeutic use Adrenergic beta-Agonists - therapeutic use Basic Science Investigations Chronic obstructive lung disease Chronic obstructive pulmonary disease Clinical trials Clinical Trials as Topic Development and progression Drug Approval Drug Combinations Drug Discovery Drug therapy Humans Management Muscarinic Antagonists - therapeutic use Patient Selection Pharmacological research Pulmonary Disease, Chronic Obstructive - drug therapy Retrospective Studies Risk Risk factors Studies
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