Vulvovaginal-gingival Lichen Planus: Association with Lichen Planopilaris and Stratified Epithelium-specific Antinuclear Antibodies
Vulvovaginal-gingival lichen planus (VVG-LP) consists of a triad of symptoms: vulval, vaginal and gingival lichen planus lesions. The aim of this study was to analyse the prevalence of lesions in various anatomical locations in patients with VVG-LP. The study included 126 consecutive patients with l...
Gespeichert in:
| Veröffentlicht in: | Acta dermato-venereologica 2016-01, Vol.96 (1), p.92-96 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 96 |
|---|---|
| container_issue | 1 |
| container_start_page | 92 |
| container_title | Acta dermato-venereologica |
| container_volume | 96 |
| creator | Olszewska, Malgorzata Banka-Wrona, Agnieszka Skrok, Anna Rakowska, Adriana Górska, Renata Solomon, Lynn W Rudnicka, Lidia |
| description | Vulvovaginal-gingival lichen planus (VVG-LP) consists of a triad of symptoms: vulval, vaginal and gingival lichen planus lesions. The aim of this study was to analyse the prevalence of lesions in various anatomical locations in patients with VVG-LP. The study included 126 consecutive patients with lichen planus. Sixteen (12.7%) patients fulfilled the criteria of VVG-LP. In 12/16 (75%) patients with VVG-LP scalp lesions were also observed. Stratified epithelium-specific antinuclear antibodies (SES-ANA) and anti-ΔNp.3α antibodies were detected in 10/16 (75%) patients with VVG-LP and in 15/110 (13.6%) patients with other forms of lichen planus (p |
| doi_str_mv | 10.2340/00015555-2141 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1760931812</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1760931812</sourcerecordid><originalsourceid>FETCH-LOGICAL-c332t-df41ac9b5e4babc40b7d0e6b790aac9625fe07b21541cd9fd87809e1a4272f643</originalsourceid><addsrcrecordid>eNpNkElPwzAQhS0EoqVw5Ipy5GLwOHYWblVVFqkSSCzXyHac1shNgp0UceaP49AWMYfZ3qeR5iF0DuSKxoxcE0KAh8AUGBygMSQcMCU8PUTjQcODOEIn3r-HkXLIjtGIJgQYBxij77febpqNWJpaWBzy0myEjRZGrXQdPVlR9_4mmnrfKCM609TRp-lW__WmNVY44yNRl9Fz5wJVGV1G8zaA2pp-jX2rVViqaFp3pu6V1cL99rIpjfan6KgS1uuzXZ2g19v5y-weLx7vHmbTBVZxTDtcVgyEyiXXTAqpGJFpSXQi05yIsE8orzRJJQXOQJV5VWZpRnINgtGUVgmLJ-hye7d1zUevfVesjVfahid00_sC0oTkMWRAA4q3qHKN905XRevMWrivAkgx-F7sfS8G3wN_sTvdy7Uu_-i90fEPY1Z_1Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1760931812</pqid></control><display><type>article</type><title>Vulvovaginal-gingival Lichen Planus: Association with Lichen Planopilaris and Stratified Epithelium-specific Antinuclear Antibodies</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Olszewska, Malgorzata ; Banka-Wrona, Agnieszka ; Skrok, Anna ; Rakowska, Adriana ; Górska, Renata ; Solomon, Lynn W ; Rudnicka, Lidia</creator><creatorcontrib>Olszewska, Malgorzata ; Banka-Wrona, Agnieszka ; Skrok, Anna ; Rakowska, Adriana ; Górska, Renata ; Solomon, Lynn W ; Rudnicka, Lidia</creatorcontrib><description>Vulvovaginal-gingival lichen planus (VVG-LP) consists of a triad of symptoms: vulval, vaginal and gingival lichen planus lesions. The aim of this study was to analyse the prevalence of lesions in various anatomical locations in patients with VVG-LP. The study included 126 consecutive patients with lichen planus. Sixteen (12.7%) patients fulfilled the criteria of VVG-LP. In 12/16 (75%) patients with VVG-LP scalp lesions were also observed. Stratified epithelium-specific antinuclear antibodies (SES-ANA) and anti-ΔNp.3α antibodies were detected in 10/16 (75%) patients with VVG-LP and in 15/110 (13.6%) patients with other forms of lichen planus (p < 0.05). In conclusion, VVG-LP is frequently associated with lichen planopilaris. The new entity may be termed "vulvovaginal-gingival-pilar lichen planus" and our study indicates that SES-ANA is a marker of this type of lichen planus with extensive, severe and refractory-to-therapy involvement of the mucous membranes, skin and scalp.</description><identifier>ISSN: 0001-5555</identifier><identifier>EISSN: 1651-2057</identifier><identifier>DOI: 10.2340/00015555-2141</identifier><identifier>PMID: 26014511</identifier><language>eng</language><publisher>Sweden</publisher><subject>Adult ; Aged ; Antibodies, Antinuclear - analysis ; Antibodies, Antinuclear - blood ; Biomarkers - analysis ; Biopsy ; Enzyme-Linked Immunosorbent Assay ; Epithelial Cells - immunology ; Female ; Fluorescent Antibody Technique ; Gingival Diseases - diagnosis ; Gingival Diseases - epidemiology ; Gingival Diseases - immunology ; Humans ; Lichen Planus, Oral - diagnosis ; Lichen Planus, Oral - epidemiology ; Lichen Planus, Oral - immunology ; Middle Aged ; Poland - epidemiology ; Prevalence ; Terminology as Topic ; Vaginal Diseases - diagnosis ; Vaginal Diseases - epidemiology ; Vaginal Diseases - immunology ; Vulvar Diseases - diagnosis ; Vulvar Diseases - epidemiology ; Vulvar Diseases - immunology ; Young Adult</subject><ispartof>Acta dermato-venereologica, 2016-01, Vol.96 (1), p.92-96</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c332t-df41ac9b5e4babc40b7d0e6b790aac9625fe07b21541cd9fd87809e1a4272f643</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,4012,27910,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26014511$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Olszewska, Malgorzata</creatorcontrib><creatorcontrib>Banka-Wrona, Agnieszka</creatorcontrib><creatorcontrib>Skrok, Anna</creatorcontrib><creatorcontrib>Rakowska, Adriana</creatorcontrib><creatorcontrib>Górska, Renata</creatorcontrib><creatorcontrib>Solomon, Lynn W</creatorcontrib><creatorcontrib>Rudnicka, Lidia</creatorcontrib><title>Vulvovaginal-gingival Lichen Planus: Association with Lichen Planopilaris and Stratified Epithelium-specific Antinuclear Antibodies</title><title>Acta dermato-venereologica</title><addtitle>Acta Derm Venereol</addtitle><description>Vulvovaginal-gingival lichen planus (VVG-LP) consists of a triad of symptoms: vulval, vaginal and gingival lichen planus lesions. The aim of this study was to analyse the prevalence of lesions in various anatomical locations in patients with VVG-LP. The study included 126 consecutive patients with lichen planus. Sixteen (12.7%) patients fulfilled the criteria of VVG-LP. In 12/16 (75%) patients with VVG-LP scalp lesions were also observed. Stratified epithelium-specific antinuclear antibodies (SES-ANA) and anti-ΔNp.3α antibodies were detected in 10/16 (75%) patients with VVG-LP and in 15/110 (13.6%) patients with other forms of lichen planus (p < 0.05). In conclusion, VVG-LP is frequently associated with lichen planopilaris. The new entity may be termed "vulvovaginal-gingival-pilar lichen planus" and our study indicates that SES-ANA is a marker of this type of lichen planus with extensive, severe and refractory-to-therapy involvement of the mucous membranes, skin and scalp.</description><subject>Adult</subject><subject>Aged</subject><subject>Antibodies, Antinuclear - analysis</subject><subject>Antibodies, Antinuclear - blood</subject><subject>Biomarkers - analysis</subject><subject>Biopsy</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Epithelial Cells - immunology</subject><subject>Female</subject><subject>Fluorescent Antibody Technique</subject><subject>Gingival Diseases - diagnosis</subject><subject>Gingival Diseases - epidemiology</subject><subject>Gingival Diseases - immunology</subject><subject>Humans</subject><subject>Lichen Planus, Oral - diagnosis</subject><subject>Lichen Planus, Oral - epidemiology</subject><subject>Lichen Planus, Oral - immunology</subject><subject>Middle Aged</subject><subject>Poland - epidemiology</subject><subject>Prevalence</subject><subject>Terminology as Topic</subject><subject>Vaginal Diseases - diagnosis</subject><subject>Vaginal Diseases - epidemiology</subject><subject>Vaginal Diseases - immunology</subject><subject>Vulvar Diseases - diagnosis</subject><subject>Vulvar Diseases - epidemiology</subject><subject>Vulvar Diseases - immunology</subject><subject>Young Adult</subject><issn>0001-5555</issn><issn>1651-2057</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkElPwzAQhS0EoqVw5Ipy5GLwOHYWblVVFqkSSCzXyHac1shNgp0UceaP49AWMYfZ3qeR5iF0DuSKxoxcE0KAh8AUGBygMSQcMCU8PUTjQcODOEIn3r-HkXLIjtGIJgQYBxij77febpqNWJpaWBzy0myEjRZGrXQdPVlR9_4mmnrfKCM609TRp-lW__WmNVY44yNRl9Fz5wJVGV1G8zaA2pp-jX2rVViqaFp3pu6V1cL99rIpjfan6KgS1uuzXZ2g19v5y-weLx7vHmbTBVZxTDtcVgyEyiXXTAqpGJFpSXQi05yIsE8orzRJJQXOQJV5VWZpRnINgtGUVgmLJ-hye7d1zUevfVesjVfahid00_sC0oTkMWRAA4q3qHKN905XRevMWrivAkgx-F7sfS8G3wN_sTvdy7Uu_-i90fEPY1Z_1Q</recordid><startdate>201601</startdate><enddate>201601</enddate><creator>Olszewska, Malgorzata</creator><creator>Banka-Wrona, Agnieszka</creator><creator>Skrok, Anna</creator><creator>Rakowska, Adriana</creator><creator>Górska, Renata</creator><creator>Solomon, Lynn W</creator><creator>Rudnicka, Lidia</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201601</creationdate><title>Vulvovaginal-gingival Lichen Planus: Association with Lichen Planopilaris and Stratified Epithelium-specific Antinuclear Antibodies</title><author>Olszewska, Malgorzata ; Banka-Wrona, Agnieszka ; Skrok, Anna ; Rakowska, Adriana ; Górska, Renata ; Solomon, Lynn W ; Rudnicka, Lidia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c332t-df41ac9b5e4babc40b7d0e6b790aac9625fe07b21541cd9fd87809e1a4272f643</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Antibodies, Antinuclear - analysis</topic><topic>Antibodies, Antinuclear - blood</topic><topic>Biomarkers - analysis</topic><topic>Biopsy</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Epithelial Cells - immunology</topic><topic>Female</topic><topic>Fluorescent Antibody Technique</topic><topic>Gingival Diseases - diagnosis</topic><topic>Gingival Diseases - epidemiology</topic><topic>Gingival Diseases - immunology</topic><topic>Humans</topic><topic>Lichen Planus, Oral - diagnosis</topic><topic>Lichen Planus, Oral - epidemiology</topic><topic>Lichen Planus, Oral - immunology</topic><topic>Middle Aged</topic><topic>Poland - epidemiology</topic><topic>Prevalence</topic><topic>Terminology as Topic</topic><topic>Vaginal Diseases - diagnosis</topic><topic>Vaginal Diseases - epidemiology</topic><topic>Vaginal Diseases - immunology</topic><topic>Vulvar Diseases - diagnosis</topic><topic>Vulvar Diseases - epidemiology</topic><topic>Vulvar Diseases - immunology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Olszewska, Malgorzata</creatorcontrib><creatorcontrib>Banka-Wrona, Agnieszka</creatorcontrib><creatorcontrib>Skrok, Anna</creatorcontrib><creatorcontrib>Rakowska, Adriana</creatorcontrib><creatorcontrib>Górska, Renata</creatorcontrib><creatorcontrib>Solomon, Lynn W</creatorcontrib><creatorcontrib>Rudnicka, Lidia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta dermato-venereologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Olszewska, Malgorzata</au><au>Banka-Wrona, Agnieszka</au><au>Skrok, Anna</au><au>Rakowska, Adriana</au><au>Górska, Renata</au><au>Solomon, Lynn W</au><au>Rudnicka, Lidia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vulvovaginal-gingival Lichen Planus: Association with Lichen Planopilaris and Stratified Epithelium-specific Antinuclear Antibodies</atitle><jtitle>Acta dermato-venereologica</jtitle><addtitle>Acta Derm Venereol</addtitle><date>2016-01</date><risdate>2016</risdate><volume>96</volume><issue>1</issue><spage>92</spage><epage>96</epage><pages>92-96</pages><issn>0001-5555</issn><eissn>1651-2057</eissn><abstract>Vulvovaginal-gingival lichen planus (VVG-LP) consists of a triad of symptoms: vulval, vaginal and gingival lichen planus lesions. The aim of this study was to analyse the prevalence of lesions in various anatomical locations in patients with VVG-LP. The study included 126 consecutive patients with lichen planus. Sixteen (12.7%) patients fulfilled the criteria of VVG-LP. In 12/16 (75%) patients with VVG-LP scalp lesions were also observed. Stratified epithelium-specific antinuclear antibodies (SES-ANA) and anti-ΔNp.3α antibodies were detected in 10/16 (75%) patients with VVG-LP and in 15/110 (13.6%) patients with other forms of lichen planus (p < 0.05). In conclusion, VVG-LP is frequently associated with lichen planopilaris. The new entity may be termed "vulvovaginal-gingival-pilar lichen planus" and our study indicates that SES-ANA is a marker of this type of lichen planus with extensive, severe and refractory-to-therapy involvement of the mucous membranes, skin and scalp.</abstract><cop>Sweden</cop><pmid>26014511</pmid><doi>10.2340/00015555-2141</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-5555 |
| ispartof | Acta dermato-venereologica, 2016-01, Vol.96 (1), p.92-96 |
| issn | 0001-5555 1651-2057 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1760931812 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Aged Antibodies, Antinuclear - analysis Antibodies, Antinuclear - blood Biomarkers - analysis Biopsy Enzyme-Linked Immunosorbent Assay Epithelial Cells - immunology Female Fluorescent Antibody Technique Gingival Diseases - diagnosis Gingival Diseases - epidemiology Gingival Diseases - immunology Humans Lichen Planus, Oral - diagnosis Lichen Planus, Oral - epidemiology Lichen Planus, Oral - immunology Middle Aged Poland - epidemiology Prevalence Terminology as Topic Vaginal Diseases - diagnosis Vaginal Diseases - epidemiology Vaginal Diseases - immunology Vulvar Diseases - diagnosis Vulvar Diseases - epidemiology Vulvar Diseases - immunology Young Adult |
| title | Vulvovaginal-gingival Lichen Planus: Association with Lichen Planopilaris and Stratified Epithelium-specific Antinuclear Antibodies |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T14%3A48%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Vulvovaginal-gingival%20Lichen%20Planus:%20Association%20with%20Lichen%20Planopilaris%20and%20Stratified%20Epithelium-specific%20Antinuclear%20Antibodies&rft.jtitle=Acta%20dermato-venereologica&rft.au=Olszewska,%20Malgorzata&rft.date=2016-01&rft.volume=96&rft.issue=1&rft.spage=92&rft.epage=96&rft.pages=92-96&rft.issn=0001-5555&rft.eissn=1651-2057&rft_id=info:doi/10.2340/00015555-2141&rft_dat=%3Cproquest_cross%3E1760931812%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1760931812&rft_id=info:pmid/26014511&rfr_iscdi=true |