Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle

Shock wave therapy (SWT) represents a clinically widely used angiogenic and thus regenerative approach for the treatment of ischaemic heart or limb disease. Despite promising results in preclinical and clinical trials, the exact mechanism of action remains unknown. Toll-like receptor 3, which is par...

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Veröffentlicht in:	Cardiovascular research 2016-02, Vol.109 (2), p.331-343
Hauptverfasser:	Holfeld, Johannes, Tepeköylü, Can, Reissig, Christin, Lobenwein, Daniela, Scheller, Bertram, Kirchmair, Elke, Kozaryn, Radoslaw, Albrecht-Schgoer, Karin, Krapf, Christoph, Zins, Karin, Urbschat, Anja, Zacharowski, Kai, Grimm, Michael, Kirchmair, Rudolf, Paulus, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Endothelial Cells - metabolism Immunity, Innate - immunology Inflammation - metabolism Ischemia - metabolism Male Mechanotransduction, Cellular - physiology Mice, Inbred C57BL Neovascularization, Pathologic - metabolism RNA, Double-Stranded - metabolism Signal Transduction Toll-Like Receptor 3 - metabolism
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