Evaluating Hydrogen Bonds and Base Stacking of Single, Tandem and Terminal GU Mismatches in RNA with a Mesoscopic Model

Guanine−Uracil (GU) mismatches are crucial to the stability of the RNA double helix and need to be considered in RNA folding algorithms for numerous biotechnological applications. Yet despite its importance, many aspects of GU base pairs are still poorly understood. There is also a lack of parametri...

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Veröffentlicht in:	Journal of chemical information and modeling 2016-01, Vol.56 (1), p.101-109
Hauptverfasser:	Amarante, Tauanne D, Weber, Gerald
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Base Pair Mismatch Base Pairing Base Sequence Guanine Hydrogen Bonding Hydrogen bonds Melting Models, Molecular Ribonucleic acid RNA RNA - chemistry RNA - genetics Uracil
Online-Zugang:	Volltext
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