Administration of Herbal Complexes, Dangguijakyak-san (TJ-23) and Coix Seeds, for Treating Verruca Planae: A Case Report
Verruca planae (VP) are warts caused by the human papillomavirus. Many patients develop resistance to the conventional therapy for these lesions. Therefore, alternative therapies are needed. We encountered a patient with VP who showed resistance to conventional therapy and was subsequently treated w...
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| Veröffentlicht in: | Explore (New York, N.Y.) N.Y.), 2016-01, Vol.12 (1), p.65-67 |
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| creator | Byun, A Ri Kwon, Seungwon Kim, Sewha |
| description | Verruca planae (VP) are warts caused by the human papillomavirus. Many patients develop resistance to the conventional therapy for these lesions. Therefore, alternative therapies are needed. We encountered a patient with VP who showed resistance to conventional therapy and was subsequently treated with Dangguijakyak-san (TJ-23; Tsumura, Japan; and Tokishakuyakusan in Japanese) and coix seed tablets with favorable outcomes. A 29-year-old woman had typical VP on her left upper extremity for >11 years. She had been receiving conventional therapies such as immunotherapy with diphenylcyclopropenone, and tretinoin and imiquimod ointments. However, her VP symptoms persisted. Therefore, she was given herbal medication therapy consisting of Dangguijakyak-san (TJ-23) and coix seeds (500mg coix seed extract; Kracie, Japan). At the four-month follow-up, the papules were found to have disappeared. Therefore, we stopped the TJ-23 + coix seed therapy. Until September 2014, the patient has had no recurrence. We believe that Dangguijakyak-san with coix seeds remedy can have an effect on the immune system and consequently treat VP. |
| doi_str_mv | 10.1016/j.explore.2015.10.003 |
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Many patients develop resistance to the conventional therapy for these lesions. Therefore, alternative therapies are needed. We encountered a patient with VP who showed resistance to conventional therapy and was subsequently treated with Dangguijakyak-san (TJ-23; Tsumura, Japan; and Tokishakuyakusan in Japanese) and coix seed tablets with favorable outcomes. A 29-year-old woman had typical VP on her left upper extremity for >11 years. She had been receiving conventional therapies such as immunotherapy with diphenylcyclopropenone, and tretinoin and imiquimod ointments. However, her VP symptoms persisted. Therefore, she was given herbal medication therapy consisting of Dangguijakyak-san (TJ-23) and coix seeds (500mg coix seed extract; Kracie, Japan). At the four-month follow-up, the papules were found to have disappeared. Therefore, we stopped the TJ-23 + coix seed therapy. Until September 2014, the patient has had no recurrence. We believe that Dangguijakyak-san with coix seeds remedy can have an effect on the immune system and consequently treat VP.</description><identifier>ISSN: 1550-8307</identifier><identifier>EISSN: 1878-7541</identifier><identifier>DOI: 10.1016/j.explore.2015.10.003</identifier><identifier>PMID: 26701790</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Alisma ; Atractylodes ; Cnidium ; Coix ; Dangguijakyaksan ; Drugs, Chinese Herbal - pharmacology ; Drugs, Chinese Herbal - therapeutic use ; Female ; Flat wart ; Humans ; Magnoliopsida ; Paeonia ; Phytotherapy ; Poria ; Seeds ; Skin - drug effects ; Skin - pathology ; TJ-23 ; Verruca planae ; Warts - drug therapy</subject><ispartof>Explore (New York, N.Y.), 2016-01, Vol.12 (1), p.65-67</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. 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Many patients develop resistance to the conventional therapy for these lesions. Therefore, alternative therapies are needed. We encountered a patient with VP who showed resistance to conventional therapy and was subsequently treated with Dangguijakyak-san (TJ-23; Tsumura, Japan; and Tokishakuyakusan in Japanese) and coix seed tablets with favorable outcomes. A 29-year-old woman had typical VP on her left upper extremity for >11 years. She had been receiving conventional therapies such as immunotherapy with diphenylcyclopropenone, and tretinoin and imiquimod ointments. However, her VP symptoms persisted. Therefore, she was given herbal medication therapy consisting of Dangguijakyak-san (TJ-23) and coix seeds (500mg coix seed extract; Kracie, Japan). At the four-month follow-up, the papules were found to have disappeared. Therefore, we stopped the TJ-23 + coix seed therapy. Until September 2014, the patient has had no recurrence. We believe that Dangguijakyak-san with coix seeds remedy can have an effect on the immune system and consequently treat VP.</description><subject>Adult</subject><subject>Alisma</subject><subject>Atractylodes</subject><subject>Cnidium</subject><subject>Coix</subject><subject>Dangguijakyaksan</subject><subject>Drugs, Chinese Herbal - pharmacology</subject><subject>Drugs, Chinese Herbal - therapeutic use</subject><subject>Female</subject><subject>Flat wart</subject><subject>Humans</subject><subject>Magnoliopsida</subject><subject>Paeonia</subject><subject>Phytotherapy</subject><subject>Poria</subject><subject>Seeds</subject><subject>Skin - drug effects</subject><subject>Skin - pathology</subject><subject>TJ-23</subject><subject>Verruca planae</subject><subject>Warts - drug therapy</subject><issn>1550-8307</issn><issn>1878-7541</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1v0zAUhi20iY3BTwD5ckiks5M6dnaDqsK-NAkEhVvrxD6p3CVxsJOp-_e4arfb3djWq-d8-CHkI2czznh5sZnhdmh9wFnOuEjZjLHiDTnlSqpMijk_Sm8hWKYKJk_Iuxg3CShFWb4lJ3kpGZcVOyXbhe1c7-IYYHS-p76hNxhqaOnSd0OLW4xf6Dfo1-vJbeDhCR6yCD09X91lefGZQm8T6Lb0N6JNZOMDXQVMvfo1_YshTAbozxZ6wEu6oEuISH_h4MP4nhw30Eb8cLjPyJ-r76vlTXb_4_p2ubjPTFp2zISyjKFETEfFjVUgZGVq1hQoG45GzeuqsmZuQIk8r5WYMwUApclrZCkozsj5vu8Q_L8J46g7Fw22aSf0U9RclqxiRSWKhIo9aoKPMWCjh-A6CE-aM72Trjf6IF3vpO_i5DTVfTqMmOoO7UvVs-UEfN0DmD766DDoaBz2Bq0LaEZtvXtlxH8TWJVs</recordid><startdate>201601</startdate><enddate>201601</enddate><creator>Byun, A Ri</creator><creator>Kwon, Seungwon</creator><creator>Kim, Sewha</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-1857-3515</orcidid></search><sort><creationdate>201601</creationdate><title>Administration of Herbal Complexes, Dangguijakyak-san (TJ-23) and Coix Seeds, for Treating Verruca Planae: A Case Report</title><author>Byun, A Ri ; Kwon, Seungwon ; Kim, Sewha</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-58d00e7ee0e791cd8a579cb0f3e7f1ec84b99dc4ca8522b85408aaa6c2be022b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Alisma</topic><topic>Atractylodes</topic><topic>Cnidium</topic><topic>Coix</topic><topic>Dangguijakyaksan</topic><topic>Drugs, Chinese Herbal - pharmacology</topic><topic>Drugs, Chinese Herbal - therapeutic use</topic><topic>Female</topic><topic>Flat wart</topic><topic>Humans</topic><topic>Magnoliopsida</topic><topic>Paeonia</topic><topic>Phytotherapy</topic><topic>Poria</topic><topic>Seeds</topic><topic>Skin - drug effects</topic><topic>Skin - pathology</topic><topic>TJ-23</topic><topic>Verruca planae</topic><topic>Warts - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Byun, A Ri</creatorcontrib><creatorcontrib>Kwon, Seungwon</creatorcontrib><creatorcontrib>Kim, Sewha</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Explore (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Byun, A Ri</au><au>Kwon, Seungwon</au><au>Kim, Sewha</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Administration of Herbal Complexes, Dangguijakyak-san (TJ-23) and Coix Seeds, for Treating Verruca Planae: A Case Report</atitle><jtitle>Explore (New York, N.Y.)</jtitle><addtitle>Explore (NY)</addtitle><date>2016-01</date><risdate>2016</risdate><volume>12</volume><issue>1</issue><spage>65</spage><epage>67</epage><pages>65-67</pages><issn>1550-8307</issn><eissn>1878-7541</eissn><abstract>Verruca planae (VP) are warts caused by the human papillomavirus. Many patients develop resistance to the conventional therapy for these lesions. Therefore, alternative therapies are needed. We encountered a patient with VP who showed resistance to conventional therapy and was subsequently treated with Dangguijakyak-san (TJ-23; Tsumura, Japan; and Tokishakuyakusan in Japanese) and coix seed tablets with favorable outcomes. A 29-year-old woman had typical VP on her left upper extremity for >11 years. She had been receiving conventional therapies such as immunotherapy with diphenylcyclopropenone, and tretinoin and imiquimod ointments. However, her VP symptoms persisted. Therefore, she was given herbal medication therapy consisting of Dangguijakyak-san (TJ-23) and coix seeds (500mg coix seed extract; Kracie, Japan). At the four-month follow-up, the papules were found to have disappeared. Therefore, we stopped the TJ-23 + coix seed therapy. Until September 2014, the patient has had no recurrence. We believe that Dangguijakyak-san with coix seeds remedy can have an effect on the immune system and consequently treat VP.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26701790</pmid><doi>10.1016/j.explore.2015.10.003</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0002-1857-3515</orcidid></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Alisma Atractylodes Cnidium Coix Dangguijakyaksan Drugs, Chinese Herbal - pharmacology Drugs, Chinese Herbal - therapeutic use Female Flat wart Humans Magnoliopsida Paeonia Phytotherapy Poria Seeds Skin - drug effects Skin - pathology TJ-23 Verruca planae Warts - drug therapy |
| title | Administration of Herbal Complexes, Dangguijakyak-san (TJ-23) and Coix Seeds, for Treating Verruca Planae: A Case Report |
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