Giant mid-esophageal diverticula successfully treated by per-oral endoscopic myotomy

Background Surgery is currently the preferred treatment choice for mid-esophageal diverticula, while endoscopic therapy is rapidly establishing itself. Method We report the first two cases of giant mid-esophageal diverticula presented with dysphagia successfully treated with per-oral endoscopic myotomy (POEM). Result There were no complications during the procedure and the patients’ conditions improved remarkably within short time of recovery. Conclusion POEM could provide a safe, effective and less invasive treatment of mid-esophageal diverticula if appropriately used. Further studies on long-term efficacy with larger number of cases are necessary.