Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and antioxidant activities

[Display omitted] A series of novel coumarin pyrazole hybrids of biological interest were synthesized from the hydrazones, carbazones and thiocarbazones via Vilsmeier Haack formylation reaction. These intermediates and formyl pyrazoles were evaluated for antimicrobial and antioxidant activities. Amo...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2016-01, Vol.26 (2), p.690-694
Hauptverfasser:	Nagamallu, Renuka, Srinivasan, Bharath, Ningappa, Mylarappa B., Kariyappa, Ajay Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - chemical synthesis Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antimicrobial Antioxidant Antioxidants - chemical synthesis Antioxidants - chemistry Antioxidants - pharmacology Bacteria - drug effects Bacterial Infections - drug therapy Coumarin Coumarins - chemical synthesis Coumarins - chemistry Coumarins - pharmacology DPPH Fungi - drug effects Humans Hydroxyl radical MIC Microbial Sensitivity Tests Mycoses - drug therapy Pyrazole Pyrazoles - chemical synthesis Pyrazoles - chemistry Pyrazoles - pharmacology Quantitative Structure-Activity Relationship
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