RING1 proteins contribute to early proximal-distal specification of the forelimb bud by restricting Meis2 expression

Polycomb group (PcG) proteins play a pivotal role in silencing developmental genes and help to maintain various stem and precursor cells and regulate their differentiation. PcG factors also regulate dynamic and complex regional specification, particularly in mammals, but this activity is mechanistic...

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Veröffentlicht in:	Development (Cambridge) 2016-01, Vol.143 (2), p.276-285
Hauptverfasser:	Yakushiji-Kaminatsui, Nayuta, Kondo, Takashi, Endo, Takaho A, Koseki, Yoko, Kondo, Kaori, Ohara, Osamu, Vidal, Miguel, Koseki, Haruhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatin Immunoprecipitation Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Female Forelimb - embryology Gene Expression Regulation, Developmental - genetics Gene Expression Regulation, Developmental - physiology Homeodomain Proteins - genetics Homeodomain Proteins - metabolism In Situ Hybridization Male Mice Mice, Mutant Strains Polycomb Repressive Complex 1 - genetics Polycomb Repressive Complex 1 - metabolism Pregnancy Retinoic Acid 4-Hydroxylase Tretinoin - pharmacology Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism
Online-Zugang:	Volltext
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