Regulatory effect of hydroquinone–tetraethylene glycol conjugates on zebrafish pigmentation

[Display omitted] We synthesized two hydroquinone–tetraethylene glycol conjugates (HQ–TGs) and investigated their logP, photophysical stability, and redox chemical stability. HQ–TGs are a little more hydrophilic than hydroquinone (HQ) and show an enhanced photophysical and redox chemical stability c...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2016-01, Vol.26 (2), p.699-705
Hauptverfasser:	Le, Hoa Thi, Hong, Bin Na, Lee, Yeong Ro, Cheon, Ji Hyun, Kang, Tong Ho, Kim, Tae Woo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cell Survival - drug effects Ethylene Glycols - chemistry Ethylene Glycols - pharmacology Hydroquinone Hydroquinones - chemistry Hydroquinones - pharmacology Hydroquinone–tetraethylene glycol conjugate Larva - drug effects Larva - physiology Models, Molecular Pigmentation Pigmentation - drug effects Skin Lightening Preparations - chemistry Skin Lightening Preparations - pharmacology Whitening effect Zebrafish Zebrafish - physiology
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