Direct and Indirect Effects of Function in Associated Variables Such as Depression and Severity on Pain Intensity in Women with Carpal Tunnel Syndrome
Objective To determine the direct and indirect effects of function on clinical variables such as age, pain intensity, years of the disease, severity of symptoms, and depression in women with electrodiagnostic and clinical diagnosis of carpal tunnel syndrome (CTS). Design A cross‐sectional study. Set...
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| Veröffentlicht in: | Pain medicine (Malden, Mass.) Mass.), 2015-12, Vol.16 (12), p.2405-2411 |
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| container_title | Pain medicine (Malden, Mass.) |
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| creator | Fernández‐de‐las‐Peñas, César Fernández‐Muñoz, Juan J. Palacios‐Ceña, María Navarro‐Pardo, Esperanza Ambite‐Quesada, Silvia Salom‐Moreno, Jaime |
| description | Objective
To determine the direct and indirect effects of function on clinical variables such as age, pain intensity, years of the disease, severity of symptoms, and depression in women with electrodiagnostic and clinical diagnosis of carpal tunnel syndrome (CTS).
Design
A cross‐sectional study.
Setting
Patients from an urban hospital referred to a university clinic.
Methods
Two hundred and forty‐four (n = 224) women with CTS were included. Demographic and clinical data, duration of symptoms, function, symptom's severity of the symptoms, pain intensity, and depression were self‐reported collected. Correlation and path analysis with maximum likelihood estimation were conducted to assess the direct and indirect effect of hand function on pain, age, years with the disease, symptoms severity, and depression.
Results
Significant positive correlations between function and pain intensity, years with pain and symptoms severity were observed. The path analysis found direct effects from depression, symptoms severity, and years with pain to function (all, P |
| doi_str_mv | 10.1111/pme.12857 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1760899917</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3929100831</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3887-9feec98ead26f0808ddcb2514835a433b8ebbd1cf22c4e40317f0a3f39e8197a3</originalsourceid><addsrcrecordid>eNp1kctO3DAUhq2qiMuURV-gssSmXQz4ksTOEg0DjAQCaWi7jBz7WBglTmonRfMifV48ZGCBVG-Of_s7vy8_Ql8pOaVpnPUtnFImc_EJHdKcFfOs4OLzbs64yA_QUYxPhNAik3wfHbCCioIReoj-XbgAesDKG7zyZhJLa1OJuLP4cvR6cJ3HzuPzGDvt1AAG_1LBqbqBiNejfsQq4gvoA8S4Rbdea_gLwQ0bnPS9Ss0rP4CP25UkfnctePzshke8UKFXDX4YvYcGrzfehLT5Be1Z1UQ43tUZ-nm5fFhcz2_urlaL85u55lKKeWkBdClBGVZYIok0Rtcsp-mVuco4ryXUtaHaMqYzyAinwhLFLS9B0lIoPkPfJ98-dH9GiEPVuqihaZSHboxV-iYiy7KkIqEnH9Cnbgw-3S5RuSxFxtKxM_RjonToYgxgqz64VoVNRUm1DatKYVWvYSX2285xrFsw7-RbOgk4m4Bn18Dm_07V_e1ysnwBmWifWg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1758974248</pqid></control><display><type>article</type><title>Direct and Indirect Effects of Function in Associated Variables Such as Depression and Severity on Pain Intensity in Women with Carpal Tunnel Syndrome</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Fernández‐de‐las‐Peñas, César ; Fernández‐Muñoz, Juan J. ; Palacios‐Ceña, María ; Navarro‐Pardo, Esperanza ; Ambite‐Quesada, Silvia ; Salom‐Moreno, Jaime</creator><creatorcontrib>Fernández‐de‐las‐Peñas, César ; Fernández‐Muñoz, Juan J. ; Palacios‐Ceña, María ; Navarro‐Pardo, Esperanza ; Ambite‐Quesada, Silvia ; Salom‐Moreno, Jaime</creatorcontrib><description>Objective
To determine the direct and indirect effects of function on clinical variables such as age, pain intensity, years of the disease, severity of symptoms, and depression in women with electrodiagnostic and clinical diagnosis of carpal tunnel syndrome (CTS).
Design
A cross‐sectional study.
Setting
Patients from an urban hospital referred to a university clinic.
Methods
Two hundred and forty‐four (n = 224) women with CTS were included. Demographic and clinical data, duration of symptoms, function, symptom's severity of the symptoms, pain intensity, and depression were self‐reported collected. Correlation and path analysis with maximum likelihood estimation were conducted to assess the direct and indirect effect of hand function on pain, age, years with the disease, symptoms severity, and depression.
Results
Significant positive correlations between function and pain intensity, years with pain and symptoms severity were observed. The path analysis found direct effects from depression, symptoms severity, and years with pain to function (all, P < 0.01). Paths between function and depression on pain intensity (both, P < 0.01) were also observed. The amount of function explained by all predictors was 22%. The indirect effects in the path analysis revealed that function exerted an indirect effect from depression to pain intensity (B = 0.18; P < 0.01), and from symptoms severity to the intensity of pain (B = 0.10; P < 0.01). Overall, the amount of current pain intensity explained by all predictors in the model was R2 = 0.22.
Conclusions
Our study demonstrated that function mediates the relationship between depression and symptoms severity with pain intensity in women with CTS. Future longitudinal studies will help to determine the clinical implications of these findings.</description><identifier>ISSN: 1526-2375</identifier><identifier>EISSN: 1526-4637</identifier><identifier>DOI: 10.1111/pme.12857</identifier><identifier>PMID: 26176201</identifier><identifier>CODEN: PMAEAP</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Adult ; Aged ; Carpal Tunnel Syndrome ; Causality ; Comorbidity ; Cross-Sectional Studies ; Depression ; Depression - diagnosis ; Depression - epidemiology ; Depression - psychology ; Female ; Function ; Humans ; Mediation ; Middle Aged ; Neuralgia - diagnosis ; Neuralgia - epidemiology ; Neuralgia - psychology ; Pain ; Pain - diagnosis ; Pain - epidemiology ; Pain - psychology ; Pain management ; Pain Measurement ; Prevalence ; Recovery of Function ; Reproducibility of Results ; Risk Factors ; Self Report ; Sensitivity and Specificity ; Severity ; Severity of Illness Index ; Spain - epidemiology ; Symptom Assessment ; Women's Health - statistics & numerical data</subject><ispartof>Pain medicine (Malden, Mass.), 2015-12, Vol.16 (12), p.2405-2411</ispartof><rights>Wiley Periodicals, Inc.</rights><rights>2015 American Academy of Pain Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3887-9feec98ead26f0808ddcb2514835a433b8ebbd1cf22c4e40317f0a3f39e8197a3</citedby><cites>FETCH-LOGICAL-c3887-9feec98ead26f0808ddcb2514835a433b8ebbd1cf22c4e40317f0a3f39e8197a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fpme.12857$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fpme.12857$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26176201$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fernández‐de‐las‐Peñas, César</creatorcontrib><creatorcontrib>Fernández‐Muñoz, Juan J.</creatorcontrib><creatorcontrib>Palacios‐Ceña, María</creatorcontrib><creatorcontrib>Navarro‐Pardo, Esperanza</creatorcontrib><creatorcontrib>Ambite‐Quesada, Silvia</creatorcontrib><creatorcontrib>Salom‐Moreno, Jaime</creatorcontrib><title>Direct and Indirect Effects of Function in Associated Variables Such as Depression and Severity on Pain Intensity in Women with Carpal Tunnel Syndrome</title><title>Pain medicine (Malden, Mass.)</title><addtitle>Pain Med</addtitle><description>Objective
To determine the direct and indirect effects of function on clinical variables such as age, pain intensity, years of the disease, severity of symptoms, and depression in women with electrodiagnostic and clinical diagnosis of carpal tunnel syndrome (CTS).
Design
A cross‐sectional study.
Setting
Patients from an urban hospital referred to a university clinic.
Methods
Two hundred and forty‐four (n = 224) women with CTS were included. Demographic and clinical data, duration of symptoms, function, symptom's severity of the symptoms, pain intensity, and depression were self‐reported collected. Correlation and path analysis with maximum likelihood estimation were conducted to assess the direct and indirect effect of hand function on pain, age, years with the disease, symptoms severity, and depression.
Results
Significant positive correlations between function and pain intensity, years with pain and symptoms severity were observed. The path analysis found direct effects from depression, symptoms severity, and years with pain to function (all, P < 0.01). Paths between function and depression on pain intensity (both, P < 0.01) were also observed. The amount of function explained by all predictors was 22%. The indirect effects in the path analysis revealed that function exerted an indirect effect from depression to pain intensity (B = 0.18; P < 0.01), and from symptoms severity to the intensity of pain (B = 0.10; P < 0.01). Overall, the amount of current pain intensity explained by all predictors in the model was R2 = 0.22.
Conclusions
Our study demonstrated that function mediates the relationship between depression and symptoms severity with pain intensity in women with CTS. Future longitudinal studies will help to determine the clinical implications of these findings.</description><subject>Adult</subject><subject>Aged</subject><subject>Carpal Tunnel Syndrome</subject><subject>Causality</subject><subject>Comorbidity</subject><subject>Cross-Sectional Studies</subject><subject>Depression</subject><subject>Depression - diagnosis</subject><subject>Depression - epidemiology</subject><subject>Depression - psychology</subject><subject>Female</subject><subject>Function</subject><subject>Humans</subject><subject>Mediation</subject><subject>Middle Aged</subject><subject>Neuralgia - diagnosis</subject><subject>Neuralgia - epidemiology</subject><subject>Neuralgia - psychology</subject><subject>Pain</subject><subject>Pain - diagnosis</subject><subject>Pain - epidemiology</subject><subject>Pain - psychology</subject><subject>Pain management</subject><subject>Pain Measurement</subject><subject>Prevalence</subject><subject>Recovery of Function</subject><subject>Reproducibility of Results</subject><subject>Risk Factors</subject><subject>Self Report</subject><subject>Sensitivity and Specificity</subject><subject>Severity</subject><subject>Severity of Illness Index</subject><subject>Spain - epidemiology</subject><subject>Symptom Assessment</subject><subject>Women's Health - statistics & numerical data</subject><issn>1526-2375</issn><issn>1526-4637</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kctO3DAUhq2qiMuURV-gssSmXQz4ksTOEg0DjAQCaWi7jBz7WBglTmonRfMifV48ZGCBVG-Of_s7vy8_Ql8pOaVpnPUtnFImc_EJHdKcFfOs4OLzbs64yA_QUYxPhNAik3wfHbCCioIReoj-XbgAesDKG7zyZhJLa1OJuLP4cvR6cJ3HzuPzGDvt1AAG_1LBqbqBiNejfsQq4gvoA8S4Rbdea_gLwQ0bnPS9Ss0rP4CP25UkfnctePzshke8UKFXDX4YvYcGrzfehLT5Be1Z1UQ43tUZ-nm5fFhcz2_urlaL85u55lKKeWkBdClBGVZYIok0Rtcsp-mVuco4ryXUtaHaMqYzyAinwhLFLS9B0lIoPkPfJ98-dH9GiEPVuqihaZSHboxV-iYiy7KkIqEnH9Cnbgw-3S5RuSxFxtKxM_RjonToYgxgqz64VoVNRUm1DatKYVWvYSX2285xrFsw7-RbOgk4m4Bn18Dm_07V_e1ysnwBmWifWg</recordid><startdate>201512</startdate><enddate>201512</enddate><creator>Fernández‐de‐las‐Peñas, César</creator><creator>Fernández‐Muñoz, Juan J.</creator><creator>Palacios‐Ceña, María</creator><creator>Navarro‐Pardo, Esperanza</creator><creator>Ambite‐Quesada, Silvia</creator><creator>Salom‐Moreno, Jaime</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201512</creationdate><title>Direct and Indirect Effects of Function in Associated Variables Such as Depression and Severity on Pain Intensity in Women with Carpal Tunnel Syndrome</title><author>Fernández‐de‐las‐Peñas, César ; Fernández‐Muñoz, Juan J. ; Palacios‐Ceña, María ; Navarro‐Pardo, Esperanza ; Ambite‐Quesada, Silvia ; Salom‐Moreno, Jaime</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3887-9feec98ead26f0808ddcb2514835a433b8ebbd1cf22c4e40317f0a3f39e8197a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Carpal Tunnel Syndrome</topic><topic>Causality</topic><topic>Comorbidity</topic><topic>Cross-Sectional Studies</topic><topic>Depression</topic><topic>Depression - diagnosis</topic><topic>Depression - epidemiology</topic><topic>Depression - psychology</topic><topic>Female</topic><topic>Function</topic><topic>Humans</topic><topic>Mediation</topic><topic>Middle Aged</topic><topic>Neuralgia - diagnosis</topic><topic>Neuralgia - epidemiology</topic><topic>Neuralgia - psychology</topic><topic>Pain</topic><topic>Pain - diagnosis</topic><topic>Pain - epidemiology</topic><topic>Pain - psychology</topic><topic>Pain management</topic><topic>Pain Measurement</topic><topic>Prevalence</topic><topic>Recovery of Function</topic><topic>Reproducibility of Results</topic><topic>Risk Factors</topic><topic>Self Report</topic><topic>Sensitivity and Specificity</topic><topic>Severity</topic><topic>Severity of Illness Index</topic><topic>Spain - epidemiology</topic><topic>Symptom Assessment</topic><topic>Women's Health - statistics & numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fernández‐de‐las‐Peñas, César</creatorcontrib><creatorcontrib>Fernández‐Muñoz, Juan J.</creatorcontrib><creatorcontrib>Palacios‐Ceña, María</creatorcontrib><creatorcontrib>Navarro‐Pardo, Esperanza</creatorcontrib><creatorcontrib>Ambite‐Quesada, Silvia</creatorcontrib><creatorcontrib>Salom‐Moreno, Jaime</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Pain medicine (Malden, Mass.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fernández‐de‐las‐Peñas, César</au><au>Fernández‐Muñoz, Juan J.</au><au>Palacios‐Ceña, María</au><au>Navarro‐Pardo, Esperanza</au><au>Ambite‐Quesada, Silvia</au><au>Salom‐Moreno, Jaime</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Direct and Indirect Effects of Function in Associated Variables Such as Depression and Severity on Pain Intensity in Women with Carpal Tunnel Syndrome</atitle><jtitle>Pain medicine (Malden, Mass.)</jtitle><addtitle>Pain Med</addtitle><date>2015-12</date><risdate>2015</risdate><volume>16</volume><issue>12</issue><spage>2405</spage><epage>2411</epage><pages>2405-2411</pages><issn>1526-2375</issn><eissn>1526-4637</eissn><coden>PMAEAP</coden><abstract>Objective
To determine the direct and indirect effects of function on clinical variables such as age, pain intensity, years of the disease, severity of symptoms, and depression in women with electrodiagnostic and clinical diagnosis of carpal tunnel syndrome (CTS).
Design
A cross‐sectional study.
Setting
Patients from an urban hospital referred to a university clinic.
Methods
Two hundred and forty‐four (n = 224) women with CTS were included. Demographic and clinical data, duration of symptoms, function, symptom's severity of the symptoms, pain intensity, and depression were self‐reported collected. Correlation and path analysis with maximum likelihood estimation were conducted to assess the direct and indirect effect of hand function on pain, age, years with the disease, symptoms severity, and depression.
Results
Significant positive correlations between function and pain intensity, years with pain and symptoms severity were observed. The path analysis found direct effects from depression, symptoms severity, and years with pain to function (all, P < 0.01). Paths between function and depression on pain intensity (both, P < 0.01) were also observed. The amount of function explained by all predictors was 22%. The indirect effects in the path analysis revealed that function exerted an indirect effect from depression to pain intensity (B = 0.18; P < 0.01), and from symptoms severity to the intensity of pain (B = 0.10; P < 0.01). Overall, the amount of current pain intensity explained by all predictors in the model was R2 = 0.22.
Conclusions
Our study demonstrated that function mediates the relationship between depression and symptoms severity with pain intensity in women with CTS. Future longitudinal studies will help to determine the clinical implications of these findings.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>26176201</pmid><doi>10.1111/pme.12857</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1526-2375 |
| ispartof | Pain medicine (Malden, Mass.), 2015-12, Vol.16 (12), p.2405-2411 |
| issn | 1526-2375 1526-4637 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1760899917 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Carpal Tunnel Syndrome Causality Comorbidity Cross-Sectional Studies Depression Depression - diagnosis Depression - epidemiology Depression - psychology Female Function Humans Mediation Middle Aged Neuralgia - diagnosis Neuralgia - epidemiology Neuralgia - psychology Pain Pain - diagnosis Pain - epidemiology Pain - psychology Pain management Pain Measurement Prevalence Recovery of Function Reproducibility of Results Risk Factors Self Report Sensitivity and Specificity Severity Severity of Illness Index Spain - epidemiology Symptom Assessment Women's Health - statistics & numerical data |
| title | Direct and Indirect Effects of Function in Associated Variables Such as Depression and Severity on Pain Intensity in Women with Carpal Tunnel Syndrome |
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