Anti-irritant and anti-inflammatory effects of glycerol and xylitol in sodium lauryl sulphate-induced acute irritation

Background Glycerol is known to possess anti‐irritant and hydrating properties and previous studies suggested that xylitol may also have similar effects. Objective Our aim was to study whether different concentrations of these polyols restore skin barrier function and soothe inflammation in sodium l...

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Veröffentlicht in:	Journal of the European Academy of Dermatology and Venereology 2015-12, Vol.29 (12), p.2333-2341
Hauptverfasser:	Szél, E., Polyánka, H., Szabó, K., Hartmann, P., Degovics, D., Balázs, B., Németh, I.B., Korponyai, C., Csányi, E., Kaszaki, J., Dikstein, S., Nagy, K., Kemény, L., Erős, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dermatitis, Irritant - drug therapy Dermatitis, Irritant - etiology Dermatitis, Irritant - pathology Emollients - pharmacology Emollients - therapeutic use Gene Expression - drug effects Glycerol - pharmacology Glycerol - therapeutic use Interleukin-1alpha - genetics Interleukin-1beta - genetics Intravital Microscopy Male Mice Mice, Hairless Permeability - drug effects Regional Blood Flow - drug effects Skin - blood supply Skin - chemistry Skin - metabolism Skin Physiological Phenomena - drug effects Sodium Dodecyl Sulfate - pharmacokinetics Tumor Necrosis Factor-alpha - genetics Water - analysis Water Loss, Insensible - drug effects Xylitol - pharmacology Xylitol - therapeutic use
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