Prevention of conversion to abnormal transcranial Doppler with hydroxyurea in sickle cell anemia: A Phase III international randomized clinical trial

Children with sickle cell anemia (SCA) and conditional transcranial Doppler (TCD) ultrasound velocities (170–199 cm/sec) may develop stroke. However, with limited available clinical data, the current standard of care for conditional TCD velocities is observation. The efficacy of hydroxyurea in preve...

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Veröffentlicht in:	American journal of hematology 2015-12, Vol.90 (12), p.1099-1105
Hauptverfasser:	Hankins, Jane S., McCarville, Mary Beth, Rankine‐Mullings, Angela, Reid, Marvin E., Lobo, Clarisse L.C., Moura, Patricia G., Ali, Susanna, Soares, Deanne P., Aldred, Karen, Jay, Dennis W., Aygun, Banu, Bennett, John, Kang, Guolian, Goldsmith, Jonathan C., Smeltzer, Matthew P., Boyett, James M., Ware, Russell E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Sickle Cell - drug therapy Antineoplastic Agents - administration & dosage Antineoplastic Agents - therapeutic use Child Child, Preschool Female Humans Hydroxyurea - administration & dosage Hydroxyurea - therapeutic use Male Ultrasonography, Doppler, Transcranial
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