Helminth Products Protect against Autoimmunity via Innate Type 2 Cytokines IL-5 and IL-33, Which Promote Eosinophilia

Epidemiologic studies in humans have demonstrated that infection with helminth parasites is associated with a reduced risk of developing autoimmune diseases. Mechanistic studies in mice have linked the protective effect of helminths on autoimmunity to the suppressive activity of helminth-induced reg...

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Veröffentlicht in:The Journal of immunology (1950) 2016-01, Vol.196 (2), p.703-714
Hauptverfasser: Finlay, Conor M, Stefanska, Anna M, Walsh, Kevin P, Kelly, Patrick J, Boon, Louis, Lavelle, Ed C, Walsh, Patrick T, Mills, Kingston H G
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Sprache:eng
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