Epididymal protein ASF is a d-galactose-specific lectin with apoptotic effect on human breast cancer cell line MCF7

•Epididymal ASF at a specified condition acts as a d-galactose specific lectin.•At the same condition ASF shows strong affinity for ECM protein fibronectin.•Binding with fibronectin ASF block fibronectin-MCF7 interaction.•Inhibiting MCF7 adhesion ASF promote adhesion dependent apoptosis to MCF7. Iso...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of biological macromolecules 2016-03, Vol.84, p.208-220
Hauptverfasser:	Roy, Debarun, Das, Kaushik, Mondal, Subhasish, Bhowmick, Debajit, Dey, Souvik, Majumder, Gopal C., Mukherjee, Biswajit, Bhattacharyya, Debdas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion dependent apoptosis Agglutinins - metabolism Animals Apoptosis Cell Adhesion Epididymal anti sticking factor Epididymis - metabolism Extracellular Matrix Extracellular Matrix Proteins - metabolism Flow Cytometry Gene Expression Glycoproteins - isolation & purification Glycoproteins - metabolism Goats Humans Hydrogen-Ion Concentration Lectins - metabolism Male MCF-7 Cells Protein Binding Soluble lectin Spermatozoa - metabolism Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!