Iron-Catalyzed CαH Oxidation of Tertiary, Aliphatic Amines to Amides under Mild Conditions

De novo syntheses of amides often generate stoichiometric amounts of waste. Thus, recent progress in the field has focused on precious metal catalyzed, oxidative protocols to generate such functionalities. However, simple tertiary alkyl amines cannot be used as starting materials in these protocols....

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Veröffentlicht in:	Angewandte Chemie International Edition 2015-12, Vol.54 (49), p.14907-14910
Hauptverfasser:	Legacy, Christopher J., Wang, Anqi, O'Day, Brian J., Emmert, Marion H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aliphatic amines Amides Amines Catalysts Chemical synthesis CH functionalization Intermediates Iron iron catalysis Lidocaine metabolite synthesis Metabolites Oxidation Reaction intermediates reaction mechanism
Online-Zugang:	Volltext
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