Effect of Artesunate–Amodiaquine on Mortality Related to Ebola Virus Disease

A shortage of artemether–lumefantrine at the Ebola treatment center in Liberia led to the use of artesunate–amodiaquine for malaria treatment during a 12-day period. In this setting, artesunate–amodiaquine use was associated with a 31% lower risk of death from Ebola. The outbreak of Ebola virus dise...

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Veröffentlicht in:	The New England journal of medicine 2016-01, Vol.374 (1), p.23-32
Hauptverfasser:	Gignoux, Etienne, Azman, Andrew S, de Smet, Martin, Azuma, Philippe, Massaquoi, Moses, Job, Dorian, Tiffany, Amanda, Petrucci, Roberta, Sterk, Esther, Potet, Julien, Suzuki, Motoi, Kurth, Andreas, Cannas, Angela, Bocquin, Anne, Strecker, Thomas, Logue, Christopher, Pottage, Thomas, Yue, Constanze, Cabrol, Jean-Clement, Serafini, Micaela, Ciglenecki, Iza
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Amodiaquine Amodiaquine - therapeutic use Anti-Bacterial Agents - therapeutic use Antimalarial agents Antimalarials - adverse effects Antimalarials - therapeutic use Artemether Artemisinins - therapeutic use Artesunate Child Child, Preschool Clinical outcomes Death Drug Combinations Drug therapy Ebola virus Ebolavirus Ethanolamines - therapeutic use Female Fluorenes - therapeutic use Hemorrhagic Fever, Ebola - complications Hemorrhagic Fever, Ebola - drug therapy Hemorrhagic Fever, Ebola - mortality Humans Infant Liberia Malaria Malaria - complications Malaria - drug therapy Male Middle Aged Mortality Patients Pharmaceuticals Regression Analysis Risk Young Adult
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