Diffuse fibrosis leads to a decrease in unipolar voltage: Validation in a swine model of premature ventricular contraction–induced cardiomyopathy

Background Frequent premature ventricular contractions (PVCs) may lead to dilated cardiomyopathy. A leftward shift in the unipolar voltage distribution in patients with cardiomyopathy has also been described and attributed to increased fibrosis. Objectives We established a swine model of PVC-induced...

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Veröffentlicht in:	Heart rhythm 2016-02, Vol.13 (2), p.547-554
Hauptverfasser:	Tanaka, Yasuaki, MD, Rahmutula, Dolkun, MD, PhD, Duggirala, Srikant, MD, Nazer, Babak, MD, Fang, Qizhi, MD, Olgin, Jeffrey, MD, Sievers, Richard, BS, Gerstenfeld, Edward P., MS, MD, FHRS
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cardiomyopathy Cardiomyopathy, Dilated - etiology Cardiomyopathy, Dilated - pathology Cardiomyopathy, Dilated - physiopathology Cardiovascular Disease Models, Animal Electroanatomic mapping Electrophysiologic Techniques, Cardiac - methods Electrophysiological Phenomena Fibrosis Humans Models, Cardiovascular Premature ventricular contraction Severity of Illness Index Stroke Volume Swine Ventricular Dysfunction, Left - etiology Ventricular Dysfunction, Left - pathology Ventricular Dysfunction, Left - physiopathology Ventricular Premature Complexes - complications Ventricular Premature Complexes - physiopathology Voltage mapping
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