Surface immobilization and bioactivity of TGF-β1 inhibitor peptides for bone implant applications

TGF-β1 is the most related cytokine with the production of fibrotic tissue. It plays an important role on the production of collagen by fibroblasts and other types of cells. The inhibition of this cytokine reduces fibrosis in various types of tissue. Biofunctionalization of dental and orthopedic imp...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2016-02, Vol.104 (2), p.385-394
Hauptverfasser:	Sevilla, Pablo, Vining, Kyle V., Dotor, Javier, Rodriguez, Daniel, Gil, F. Javier, Aparicio, Conrado
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals biofunctionalization Cell Line Coated Materials, Biocompatible - chemistry Dental Implants Humans Immobilized Proteins - chemistry Implants, Experimental Mice Peptides - chemistry silanization surface modification TGF-β inhibitor peptides titanium Transforming Growth Factor beta1 - antagonists & inhibitors
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