SDPR functions as a metastasis suppressor in breast cancer by promoting apoptosis

Metastatic dissemination of breast cancer cells represents a significant clinical obstacle to curative therapy. The loss of function of metastasis suppressor genes is a major rate-limiting step in breast cancer progression that prevents the formation of new colonies at distal sites. However, the dis...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2016-01, Vol.113 (3), p.638-643
Hauptverfasser:	Ozturk, Sait, Papageorgis, Panagiotis, Wong, Chen Khuan, Lambert, Arthur W., Abdolmaleky, Hamid M., Thiagalingam, Arunthathi, Cohen, Herbert T., Thiagalingam, Sam
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - genetics Biological Sciences Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Carrier Proteins - genetics Carrier Proteins - metabolism Cell Line, Tumor Cell Movement - genetics Cells Disease Progression Down-Regulation - genetics Epigenesis, Genetic Epigenetics Female Gene expression Gene Expression Regulation, Neoplastic Humans Lung Neoplasms - secondary Metastasis Mice, Inbred NOD Proteins
Online-Zugang:	Volltext
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