Donor-specific HLA alloantibodies: Impact on cardiac allograft vasculopathy, rejection, and survival after pediatric heart transplantation

Background There is increasing evidence that donor-specific anti-HLA antibodies (DSA) are associated with poor outcomes after cardiac transplantation in adults, but data are limited in children. The objective of this study was to examine the development and consequences of de novo DSA in pediatric r...

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Veröffentlicht in:	The Journal of heart and lung transplantation 2016-01, Vol.35 (1), p.87-91
Hauptverfasser:	Tran, Andrew, MD, Fixler, David, MD, Huang, Rong, MS, Meza, Tiffany, MBA, MHSM, Lacelle, Chantale, PhD, Das, Bibhuti B., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Allografts B-Lymphocytes - immunology cardiac allograft vasculopathy Child Child, Preschool Coronary Artery Disease - immunology Coronary Artery Disease - mortality Coronary Artery Disease - pathology donor-specific anti-HLA antibodies Female Follow-Up Studies Graft Rejection - immunology Graft Rejection - mortality Graft Rejection - pathology Graft Survival heart transplantation Heart Transplantation - mortality Histocompatibility Testing HLA Antigens - immunology Humans Infant Isoantibodies - immunology Male pediatrics rejections Retrospective Studies Surgery survival Survival Rate - trends Texas - epidemiology Time Factors Tissue Donors
Online-Zugang:	Volltext
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