Seroprevalence of Leishmania infection among asymptomatic renal transplant recipients from southern Spain

Background The aim of this article is to assess the seroprevalence of Leishmania infection among asymptomatic renal transplant recipients in a population in the south of Spain. Methods Serum samples were screened for immunoglobulin‐G antibodies against Leishmania with an indirect fluorescent antibod...

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Veröffentlicht in:Transplant infectious disease 2015-12, Vol.17 (6), p.795-799
Hauptverfasser: Elmahallawy, E.K., Cuadros-Moronta, E., Liébana-Martos, M.C., Rodríguez-Granger, J.M., Sampedro-Martínez, A., Agil, A., Navarro-Mari, J.M., Bravo-Soto, J., Gutierrez-Fernández, J.
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container_end_page 799
container_issue 6
container_start_page 795
container_title Transplant infectious disease
container_volume 17
creator Elmahallawy, E.K.
Cuadros-Moronta, E.
Liébana-Martos, M.C.
Rodríguez-Granger, J.M.
Sampedro-Martínez, A.
Agil, A.
Navarro-Mari, J.M.
Bravo-Soto, J.
Gutierrez-Fernández, J.
description Background The aim of this article is to assess the seroprevalence of Leishmania infection among asymptomatic renal transplant recipients in a population in the south of Spain. Methods Serum samples were screened for immunoglobulin‐G antibodies against Leishmania with an indirect fluorescent antibody test. Results Of 625 examined serum samples, 30 (4.8%) samples were positive for Leishmania antibodies. Thirteen samples showed titers of 1:80, 15 samples showed titers of 1:160, and 2 samples showed titers of 1:320. None of the patients with positive serology to Leishmania showed signs or symptoms compatible with leishmaniasis. Conclusion The prevalence of Leishmania infection found among asymptomatic renal transplant patients reinforces the need for attention in evaluation of these patients in endemic areas.
doi_str_mv 10.1111/tid.12444
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Methods Serum samples were screened for immunoglobulin‐G antibodies against Leishmania with an indirect fluorescent antibody test. Results Of 625 examined serum samples, 30 (4.8%) samples were positive for Leishmania antibodies. Thirteen samples showed titers of 1:80, 15 samples showed titers of 1:160, and 2 samples showed titers of 1:320. None of the patients with positive serology to Leishmania showed signs or symptoms compatible with leishmaniasis. Conclusion The prevalence of Leishmania infection found among asymptomatic renal transplant patients reinforces the need for attention in evaluation of these patients in endemic areas.</description><identifier>ISSN: 1398-2273</identifier><identifier>EISSN: 1399-3062</identifier><identifier>DOI: 10.1111/tid.12444</identifier><identifier>PMID: 26288113</identifier><language>eng</language><publisher>Denmark: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Protozoan - blood ; Child ; Female ; Health risk assessment ; Humans ; Infections ; Kidney Transplantation - adverse effects ; leishmaniasis ; Leishmaniasis - blood ; Leishmaniasis - epidemiology ; Male ; Middle Aged ; renal transplant recipient ; Seroepidemiologic Studies ; seroprevalence ; Spain - epidemiology ; Transplants &amp; implants ; Young Adult</subject><ispartof>Transplant infectious disease, 2015-12, Vol.17 (6), p.795-799</ispartof><rights>2015 John Wiley &amp; Sons A/S. 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Methods Serum samples were screened for immunoglobulin‐G antibodies against Leishmania with an indirect fluorescent antibody test. Results Of 625 examined serum samples, 30 (4.8%) samples were positive for Leishmania antibodies. Thirteen samples showed titers of 1:80, 15 samples showed titers of 1:160, and 2 samples showed titers of 1:320. None of the patients with positive serology to Leishmania showed signs or symptoms compatible with leishmaniasis. 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subjects Adolescent
Adult
Aged
Aged, 80 and over
Antibodies, Protozoan - blood
Child
Female
Health risk assessment
Humans
Infections
Kidney Transplantation - adverse effects
leishmaniasis
Leishmaniasis - blood
Leishmaniasis - epidemiology
Male
Middle Aged
renal transplant recipient
Seroepidemiologic Studies
seroprevalence
Spain - epidemiology
Transplants & implants
Young Adult
title Seroprevalence of Leishmania infection among asymptomatic renal transplant recipients from southern Spain
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