In vitro anti-HIV-1 virucidal activity of tyrosine-conjugated tri- and dihydroxy bile salt derivatives

The cellular toxicity and anti-human immunodeficiency virus type 1 (HIV-1) virucidal activity of four synthesized tyrosine-conjugated bile salt derivatives with high surfactant activities, namely di-iodo-deoxycholyltyrosine (DIDCT), di-iodo-chenodeoxycholyltyrosine (DICDCT), di-iodo-cholylglycyltyro...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2000-05, Vol.45 (5), p.617-621
Hauptverfasser:	Al-Jabri, A. A., Wigg, M. D., Elias, E., Lambkin, R., Mills, C. O., Oxford, J. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - chemistry Anti-HIV Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents bile salts Biological and medical sciences Cell Line Cholic Acids - chemistry Cholic Acids - pharmacology Deoxycholic Acid - analogs & derivatives Deoxycholic Acid - pharmacology deoxycholyltyrosine Detergents - pharmacology diiodochenodeoxycholyltyrosine diiodocholylglycyltyrosine diiododeoxycholyltyrosine HIV-1 - drug effects HIV-1 - physiology Human immunodeficiency virus 1 Humans Medical sciences Nonoxynol - pharmacology Pharmacology. Drug treatments Structure-Activity Relationship Surface-Active Agents - pharmacology tyrosine Tyrosine - chemistry
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