A Bacterial G Protein-Mediated Response to Replication Arrest

To define factors in E. coli promoting survival to replication fork stress, we isolated insertion mutants sensitive to replication inhibitors. One insertion caused partial loss of the universally conserved GTPase, obgE/ yhbZ gene. Although obgE is essential for growth, our insertion allele supported...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular cell 2005-02, Vol.17 (4), p.549-560
Hauptverfasser:	Foti, James J., Schienda, Jaclyn, Sutera, Vincent A., Lovett, Susan T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Cell Survival Chromosome Breakage Chromosomes, Bacterial - physiology DNA Helicases - metabolism DNA Replication Escherichia coli - genetics Escherichia coli - growth & development Escherichia coli - metabolism Escherichia coli Proteins - chemistry Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Exodeoxyribonuclease V - metabolism Flow Cytometry Genes, Dominant GTP Phosphohydrolases - chemistry GTP Phosphohydrolases - genetics GTP Phosphohydrolases - metabolism Monomeric GTP-Binding Proteins - chemistry Monomeric GTP-Binding Proteins - genetics Monomeric GTP-Binding Proteins - metabolism Mutagenesis, Insertional Mutation Phenotype
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!