Brain substrates for increased drug seeking during protracted withdrawal

Studies are reviewed indicating that both increased anxiety and altered hedonic processing accompany protracted withdrawal from opiates. Increased anxiety may be most apparent in response to stress, whereas decreased motivation for natural rewards but increased interest in drugs reveals substantial...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuropharmacology 2004, Vol.47, p.167-179
Hauptverfasser:	Aston-Jones, Gary, Harris, Glenda C.
Format:	Artikel
Sprache:	eng
Schlagworte:	A2 neurons Amygdala - metabolism Anhedonia Animals Anxiety Anxiety - etiology Bed nucleus of the stria terminalis Brain Chemistry - physiology Dopamine Dopamine - physiology Genes, fos - genetics Hedonia Humans Neuronal Plasticity - physiology Norepinephrine Norepinephrine - physiology Opioid-Related Disorders - metabolism Opioid-Related Disorders - psychology Rats Reinforcement (Psychology) Substance Withdrawal Syndrome - metabolism Substance Withdrawal Syndrome - psychology Substance-Related Disorders - metabolism Substance-Related Disorders - psychology Ventral tegmental area
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!