beta 2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration

Activation of the mesolimbic dopamine system is a critical component underlying addictive behaviors, including smoking. It has been hypothesized that the initial effect of nicotine on the dopamine system is to activate high affinity nicotinic acetylcholine receptors (nAChRs) containing the beta 2 su...

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Veröffentlicht in:	Neuropharmacology 2004-01, Vol.47, p.132-139
Hauptverfasser:	King, S L, Caldarone, B J, Picciotto, M R
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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