Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1 ) product

The product of the Wilms' tumor gene WT1 is a transcription factor overexpressed not only in leukemic blast cells of almost all patients with acute myeloid leukemia, acute lymphoid leukemia, and chronic myeloid leukemia, but also in various types of solid tumor cells. Thus, it is suggested that...

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Veröffentlicht in:	Immunogenetics (New York) 2000-02, Vol.51 (2), p.99-107
Hauptverfasser:	Oka, Y, Elisseeva, O A, Tsuboi, A, Ogawa, H, Tamaki, H, Li, H, Oji, Y, Kim, E H, Soma, T, Asada, M, Ueda, K, Maruya, E, Saji, H, Kishimoto, T, Udaka, K, Sugiyama, H
Format:	Artikel
Sprache:	eng
Schlagworte:	CD3 Complex - metabolism CD8-Positive T-Lymphocytes - cytology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism Cells, Cultured Cytotoxicity Tests, Immunologic DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - immunology Epitopes - immunology Flow Cytometry histocompatibility antigen HLA HLA-A2 Antigen - immunology HLA-A2 Antigen - metabolism Humans Immunity, Cellular - immunology Leukemia - immunology Leukemia - pathology leukemogenesis Leukocytes, Mononuclear - cytology Leukocytes, Mononuclear - immunology Peptide Fragments - chemical synthesis Peptide Fragments - immunology Peptide Fragments - metabolism Protein Binding - immunology T-Lymphocytes, Cytotoxic - cytology T-Lymphocytes, Cytotoxic - immunology T-Lymphocytes, Cytotoxic - metabolism Transcription Factors - biosynthesis Transcription Factors - immunology Wilms' tumor WT1 gene WT1 Proteins
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