Oxidative Stress Augments the Production of Matrix Metalloproteinase-1, Cyclooxygenase-2, and Prostaglandin E sub(2) through Enhancement of NF- Kappa B Activity in Lipopolysaccharide-Activated Human Primary Monocytes

The excessive production of reactive oxidative species (ROS) associated with inflammation leads to a condition of oxidative stress. Cyclooxygenase-2 (COX-2), PGE sub(2), and matrix metalloproteinases (MMPs) are important mediators during the process of inflammation. In this paper we report on studie...

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Veröffentlicht in:	The Journal of immunology (1950) 2005-10, Vol.175 (8), p.5423-5429
Hauptverfasser:	Lu, Yunbiao, Wahl, Larry M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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