Decreased copper-zinc superoxide dismutase activity and increased resistance to oxidative stress in glia maturation factor-null astrocytes

Glia maturation factor (GMF) is a highly conserved protein found mainly in the nervous system. The current work was undertaken to investigate the effect of GMF expression in astrocytes on CuZn superoxide dismutase (CuZnSOD or SOD I) and on the vulnerability of the cells to H2O2 toxicity. Primary ast...

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Veröffentlicht in:Neurochemical research 2004-08, Vol.29 (8), p.1473-1480
Hauptverfasser: Zaheer, Asgar, Yang, Baoli, Cao, Xiao, Lim, Ramon
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Sprache:eng
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