Antifungals: mechanism of action and resistance, established and novel drugs

Serious fungal infections, caused mostly by opportunistic species, are increasingly common in immunocompromised and other vulnerable patients. The use of antifungal drugs, primarily azoles and polyenes, has increased in parallel. Yet, established agents do not satisfy the medical need completely; az...

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Veröffentlicht in:	Current opinion in microbiology 1998-10, Vol.1 (5), p.547-557
1. Verfasser:	Georgopapadakou, Nafsika H
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antifungal Agents - pharmacology Antifungal Agents - therapeutic use Azoles - pharmacology Drug Evaluation Drug Industry - trends Drug Resistance, Microbial Ergosterol - biosynthesis Humans Mycoses - drug therapy Peptides Protein Synthesis Inhibitors - pharmacology Proton-Translocating ATPases - antagonists & inhibitors Sphingolipids - biosynthesis
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