Accumulation and tissue distribution of selected polychlorinated biphenyl congeners in chickens
During one to three consecutive periods of 2 weeks, broiler chickens ( n = 108) received test diets to which different amounts of PCBs (7 congeners) were added. The relationship between exposure time and accumulation of individual congeners in different chicken tissues, such as breast, thigh and abd...
Gespeichert in:
| Veröffentlicht in: | Chemosphere (Oxford) 2004-10, Vol.57 (1), p.61-66 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 66 |
|---|---|
| container_issue | 1 |
| container_start_page | 61 |
| container_title | Chemosphere (Oxford) |
| container_volume | 57 |
| creator | Maervoet, J. Chu, S.G. De Vos, S. Covaci, A. Voorspoels, S. De Schrijver, R. Schepens, P. |
| description | During one to three consecutive periods of 2 weeks, broiler chickens (
n
=
108) received test diets to which different amounts of PCBs (7 congeners) were added. The relationship between exposure time and accumulation of individual congeners in different chicken tissues, such as breast, thigh and abdominal fat tissue, was observed. In all tissues, the vast majority of the PCB accumulation occurred during the first 2 weeks of exposure. After that, PCB concentrations only increased in the abdominal fat tissue of the animals. The individual PCBs were distributed differently in the various tissues. While CBs 28, 118, 138, 153 and 180 accumulated in the chickens, CBs 52 and 101 were metabolized, but no methyl sulphone metabolites of these congeners could be detected. Our results provide information on the absorption, tissue distribution and biotransformation of the individual PCB congeners and confirm the structure–activity relationships for metabolism of PCBs in birds, which are different from those in fish or mammalian species. |
| doi_str_mv | 10.1016/j.chemosphere.2004.06.015 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_17582922</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0045653504004643</els_id><sourcerecordid>14710002</sourcerecordid><originalsourceid>FETCH-LOGICAL-c489t-a3d323598d6936be03a931c398769199cbcfcad77ad1a5acea7dbefb3baccb163</originalsourceid><addsrcrecordid>eNqNkU9v1DAQxS1ERZfCV4BwgFuCHcdOfKxW_JMqcWh7tpzxpOslsRc7qbTfHqe7Er3BaTTj3xuP3iPkA6MVo0x-3lewwymkww4jVjWlTUVlRZl4QTasa1XJatW9JJv8IEopuLgkr1PaU5rFQr0ilyzPpKrFhuhrgGVaRjO74AvjbTG7lBYsrEtzdP3yNA9DkXBEmNEWhzAeYTeG6LxZ-97lM_xxLCD4B_QYU-F8ATsHv9CnN-RiMGPCt-d6Re6_frnbfi9vfn77sb2-KaHp1FwabnnNheqsVFz2SLlRnAFXXSsVUwp6GMDYtjWWGWEATWt7HHreG4CeSX5FPp32HmL4vWCa9eQS4Dgaj2FJmrWiq1Vd_xtsWpaNWkF1AiGGlCIO-hDdZOJRM6rXGPReP4tBrzFoKnWOIWvfnT9Z-gntX-XZ9wx8PAMmgRmHaDy49IxTXcNFk7n3J24wQZuHmJn725oyTqnquKTrpu2JwOzuo8OoEzj0gNbFHJi2wf3HwX8A-1i4Vg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14710002</pqid></control><display><type>article</type><title>Accumulation and tissue distribution of selected polychlorinated biphenyl congeners in chickens</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Maervoet, J. ; Chu, S.G. ; De Vos, S. ; Covaci, A. ; Voorspoels, S. ; De Schrijver, R. ; Schepens, P.</creator><creatorcontrib>Maervoet, J. ; Chu, S.G. ; De Vos, S. ; Covaci, A. ; Voorspoels, S. ; De Schrijver, R. ; Schepens, P.</creatorcontrib><description>During one to three consecutive periods of 2 weeks, broiler chickens (
n
=
108) received test diets to which different amounts of PCBs (7 congeners) were added. The relationship between exposure time and accumulation of individual congeners in different chicken tissues, such as breast, thigh and abdominal fat tissue, was observed. In all tissues, the vast majority of the PCB accumulation occurred during the first 2 weeks of exposure. After that, PCB concentrations only increased in the abdominal fat tissue of the animals. The individual PCBs were distributed differently in the various tissues. While CBs 28, 118, 138, 153 and 180 accumulated in the chickens, CBs 52 and 101 were metabolized, but no methyl sulphone metabolites of these congeners could be detected. Our results provide information on the absorption, tissue distribution and biotransformation of the individual PCB congeners and confirm the structure–activity relationships for metabolism of PCBs in birds, which are different from those in fish or mammalian species.</description><identifier>ISSN: 0045-6535</identifier><identifier>EISSN: 1879-1298</identifier><identifier>DOI: 10.1016/j.chemosphere.2004.06.015</identifier><identifier>PMID: 15356925</identifier><identifier>CODEN: CMSHAF</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>abdominal fat ; Absorption ; Analysis of Variance ; Animal Feed - analysis ; Animal productions ; Animals ; bioaccumulation ; Biological and medical sciences ; biotransformation ; Biotransformation - physiology ; Birds ; body fat ; Chicken ; chickens ; Chickens - metabolism ; Chromatography, Gas ; feed contamination ; feed intake ; Food Contamination - analysis ; Fundamental and applied biological sciences. Psychology ; ingestion ; Metabolism ; metabolites ; Methyl sulfone ; oral administration ; PCBs ; polychlorinated biphenyls ; Polychlorinated Biphenyls - metabolism ; Polychlorinated Biphenyls - pharmacokinetics ; skeletal muscle ; Terrestrial animal productions ; Time Factors ; Tissue Distribution ; Vertebrates</subject><ispartof>Chemosphere (Oxford), 2004-10, Vol.57 (1), p.61-66</ispartof><rights>2004 Elsevier Ltd</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c489t-a3d323598d6936be03a931c398769199cbcfcad77ad1a5acea7dbefb3baccb163</citedby><cites>FETCH-LOGICAL-c489t-a3d323598d6936be03a931c398769199cbcfcad77ad1a5acea7dbefb3baccb163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.chemosphere.2004.06.015$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15984354$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15356925$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Maervoet, J.</creatorcontrib><creatorcontrib>Chu, S.G.</creatorcontrib><creatorcontrib>De Vos, S.</creatorcontrib><creatorcontrib>Covaci, A.</creatorcontrib><creatorcontrib>Voorspoels, S.</creatorcontrib><creatorcontrib>De Schrijver, R.</creatorcontrib><creatorcontrib>Schepens, P.</creatorcontrib><title>Accumulation and tissue distribution of selected polychlorinated biphenyl congeners in chickens</title><title>Chemosphere (Oxford)</title><addtitle>Chemosphere</addtitle><description>During one to three consecutive periods of 2 weeks, broiler chickens (
n
=
108) received test diets to which different amounts of PCBs (7 congeners) were added. The relationship between exposure time and accumulation of individual congeners in different chicken tissues, such as breast, thigh and abdominal fat tissue, was observed. In all tissues, the vast majority of the PCB accumulation occurred during the first 2 weeks of exposure. After that, PCB concentrations only increased in the abdominal fat tissue of the animals. The individual PCBs were distributed differently in the various tissues. While CBs 28, 118, 138, 153 and 180 accumulated in the chickens, CBs 52 and 101 were metabolized, but no methyl sulphone metabolites of these congeners could be detected. Our results provide information on the absorption, tissue distribution and biotransformation of the individual PCB congeners and confirm the structure–activity relationships for metabolism of PCBs in birds, which are different from those in fish or mammalian species.</description><subject>abdominal fat</subject><subject>Absorption</subject><subject>Analysis of Variance</subject><subject>Animal Feed - analysis</subject><subject>Animal productions</subject><subject>Animals</subject><subject>bioaccumulation</subject><subject>Biological and medical sciences</subject><subject>biotransformation</subject><subject>Biotransformation - physiology</subject><subject>Birds</subject><subject>body fat</subject><subject>Chicken</subject><subject>chickens</subject><subject>Chickens - metabolism</subject><subject>Chromatography, Gas</subject><subject>feed contamination</subject><subject>feed intake</subject><subject>Food Contamination - analysis</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>ingestion</subject><subject>Metabolism</subject><subject>metabolites</subject><subject>Methyl sulfone</subject><subject>oral administration</subject><subject>PCBs</subject><subject>polychlorinated biphenyls</subject><subject>Polychlorinated Biphenyls - metabolism</subject><subject>Polychlorinated Biphenyls - pharmacokinetics</subject><subject>skeletal muscle</subject><subject>Terrestrial animal productions</subject><subject>Time Factors</subject><subject>Tissue Distribution</subject><subject>Vertebrates</subject><issn>0045-6535</issn><issn>1879-1298</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU9v1DAQxS1ERZfCV4BwgFuCHcdOfKxW_JMqcWh7tpzxpOslsRc7qbTfHqe7Er3BaTTj3xuP3iPkA6MVo0x-3lewwymkww4jVjWlTUVlRZl4QTasa1XJatW9JJv8IEopuLgkr1PaU5rFQr0ilyzPpKrFhuhrgGVaRjO74AvjbTG7lBYsrEtzdP3yNA9DkXBEmNEWhzAeYTeG6LxZ-97lM_xxLCD4B_QYU-F8ATsHv9CnN-RiMGPCt-d6Re6_frnbfi9vfn77sb2-KaHp1FwabnnNheqsVFz2SLlRnAFXXSsVUwp6GMDYtjWWGWEATWt7HHreG4CeSX5FPp32HmL4vWCa9eQS4Dgaj2FJmrWiq1Vd_xtsWpaNWkF1AiGGlCIO-hDdZOJRM6rXGPReP4tBrzFoKnWOIWvfnT9Z-gntX-XZ9wx8PAMmgRmHaDy49IxTXcNFk7n3J24wQZuHmJn725oyTqnquKTrpu2JwOzuo8OoEzj0gNbFHJi2wf3HwX8A-1i4Vg</recordid><startdate>20041001</startdate><enddate>20041001</enddate><creator>Maervoet, J.</creator><creator>Chu, S.G.</creator><creator>De Vos, S.</creator><creator>Covaci, A.</creator><creator>Voorspoels, S.</creator><creator>De Schrijver, R.</creator><creator>Schepens, P.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>7U7</scope></search><sort><creationdate>20041001</creationdate><title>Accumulation and tissue distribution of selected polychlorinated biphenyl congeners in chickens</title><author>Maervoet, J. ; Chu, S.G. ; De Vos, S. ; Covaci, A. ; Voorspoels, S. ; De Schrijver, R. ; Schepens, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c489t-a3d323598d6936be03a931c398769199cbcfcad77ad1a5acea7dbefb3baccb163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>abdominal fat</topic><topic>Absorption</topic><topic>Analysis of Variance</topic><topic>Animal Feed - analysis</topic><topic>Animal productions</topic><topic>Animals</topic><topic>bioaccumulation</topic><topic>Biological and medical sciences</topic><topic>biotransformation</topic><topic>Biotransformation - physiology</topic><topic>Birds</topic><topic>body fat</topic><topic>Chicken</topic><topic>chickens</topic><topic>Chickens - metabolism</topic><topic>Chromatography, Gas</topic><topic>feed contamination</topic><topic>feed intake</topic><topic>Food Contamination - analysis</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>ingestion</topic><topic>Metabolism</topic><topic>metabolites</topic><topic>Methyl sulfone</topic><topic>oral administration</topic><topic>PCBs</topic><topic>polychlorinated biphenyls</topic><topic>Polychlorinated Biphenyls - metabolism</topic><topic>Polychlorinated Biphenyls - pharmacokinetics</topic><topic>skeletal muscle</topic><topic>Terrestrial animal productions</topic><topic>Time Factors</topic><topic>Tissue Distribution</topic><topic>Vertebrates</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maervoet, J.</creatorcontrib><creatorcontrib>Chu, S.G.</creatorcontrib><creatorcontrib>De Vos, S.</creatorcontrib><creatorcontrib>Covaci, A.</creatorcontrib><creatorcontrib>Voorspoels, S.</creatorcontrib><creatorcontrib>De Schrijver, R.</creatorcontrib><creatorcontrib>Schepens, P.</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Toxicology Abstracts</collection><jtitle>Chemosphere (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maervoet, J.</au><au>Chu, S.G.</au><au>De Vos, S.</au><au>Covaci, A.</au><au>Voorspoels, S.</au><au>De Schrijver, R.</au><au>Schepens, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Accumulation and tissue distribution of selected polychlorinated biphenyl congeners in chickens</atitle><jtitle>Chemosphere (Oxford)</jtitle><addtitle>Chemosphere</addtitle><date>2004-10-01</date><risdate>2004</risdate><volume>57</volume><issue>1</issue><spage>61</spage><epage>66</epage><pages>61-66</pages><issn>0045-6535</issn><eissn>1879-1298</eissn><coden>CMSHAF</coden><abstract>During one to three consecutive periods of 2 weeks, broiler chickens (
n
=
108) received test diets to which different amounts of PCBs (7 congeners) were added. The relationship between exposure time and accumulation of individual congeners in different chicken tissues, such as breast, thigh and abdominal fat tissue, was observed. In all tissues, the vast majority of the PCB accumulation occurred during the first 2 weeks of exposure. After that, PCB concentrations only increased in the abdominal fat tissue of the animals. The individual PCBs were distributed differently in the various tissues. While CBs 28, 118, 138, 153 and 180 accumulated in the chickens, CBs 52 and 101 were metabolized, but no methyl sulphone metabolites of these congeners could be detected. Our results provide information on the absorption, tissue distribution and biotransformation of the individual PCB congeners and confirm the structure–activity relationships for metabolism of PCBs in birds, which are different from those in fish or mammalian species.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>15356925</pmid><doi>10.1016/j.chemosphere.2004.06.015</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0045-6535 |
| ispartof | Chemosphere (Oxford), 2004-10, Vol.57 (1), p.61-66 |
| issn | 0045-6535 1879-1298 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_17582922 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | abdominal fat Absorption Analysis of Variance Animal Feed - analysis Animal productions Animals bioaccumulation Biological and medical sciences biotransformation Biotransformation - physiology Birds body fat Chicken chickens Chickens - metabolism Chromatography, Gas feed contamination feed intake Food Contamination - analysis Fundamental and applied biological sciences. Psychology ingestion Metabolism metabolites Methyl sulfone oral administration PCBs polychlorinated biphenyls Polychlorinated Biphenyls - metabolism Polychlorinated Biphenyls - pharmacokinetics skeletal muscle Terrestrial animal productions Time Factors Tissue Distribution Vertebrates |
| title | Accumulation and tissue distribution of selected polychlorinated biphenyl congeners in chickens |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T13%3A23%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Accumulation%20and%20tissue%20distribution%20of%20selected%20polychlorinated%20biphenyl%20congeners%20in%20chickens&rft.jtitle=Chemosphere%20(Oxford)&rft.au=Maervoet,%20J.&rft.date=2004-10-01&rft.volume=57&rft.issue=1&rft.spage=61&rft.epage=66&rft.pages=61-66&rft.issn=0045-6535&rft.eissn=1879-1298&rft.coden=CMSHAF&rft_id=info:doi/10.1016/j.chemosphere.2004.06.015&rft_dat=%3Cproquest_cross%3E14710002%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14710002&rft_id=info:pmid/15356925&rft_els_id=S0045653504004643&rfr_iscdi=true |