Effectiveness and toxicity of high-dose cyclophosphamide in obese versus non-obese patients receiving allogeneic hematopoietic stem cell transplant

Purpose To determine if there is a difference in toxicity and effectiveness between obese and non-obese patients who receive high-dose cyclophosphamide (Cy) prior to allogeneic hematopoietic stem cell transplant (allo-HCT). Methods Patients were included in this study if they were at least 18 years...

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Veröffentlicht in:	Journal of oncology pharmacy practice 2016-02, Vol.22 (1), p.54-59
Hauptverfasser:	Hunter, Melissa R, Sabo, Roy T, McCarty, John M, Newland, Ashley M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Busulfan - therapeutic use Cyclophosphamide - administration & dosage Cyclophosphamide - adverse effects Female Graft vs Host Disease - drug therapy Hematopoietic Stem Cell Transplantation - methods Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - adverse effects Male Obesity - physiopathology Retrospective Studies Transplantation Conditioning - methods Transplantation, Homologous - methods Whole-Body Irradiation - methods
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