The Elp2 Subunit of Elongator and Elongating RNA Polymerase II Holoenzyme Is a WD40 Repeat Protein

A novel yeast gene, ELP2, is shown to encode the 90-kDa subunit of the Elongator complex and elongating RNA polymerase II holoenzyme. ELP2 encodes a protein with eight WD40 repeats, and cells lacking the gene display typicalelp phenotypes, such as temperature and salt sensitivity. Generally, differe...

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