Sodium thiosulfate protects against acrylonitrile-induced elevation of glial fibrillary acidic protein levels by replenishing glutathione

Acrylonitrile (ACN) like many organic solvents produce neurotoxicity by elevating brain glial fibrillary acidic protein (GFAP), a putative biomarker of astrogliosis. In this study we tested the hypothesis that sodium thiosulfate (STS) protective action against ACN-induced astrogliosis is glutathione...

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Veröffentlicht in:	Environmental toxicology and pharmacology 2000, Vol.8 (2), p.153-161
Hauptverfasser:	Enongene, Evaristus N, Sun, Pei N, Mehta, Chander S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylonitrile Brain GFAP GSH Neurotoxicity sodium thiosulfate STS thiosulfate
Online-Zugang:	Volltext
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