Prenatal alcohol exposure increases TNFα-induced cytotoxicity in primary astrocytes

We examined the effect of prenatal alcohol exposure (PAE) on tumor necrosis factor-α-(TNFα) induced cell death in primary astrocyte cultures. Flow cytometry revealed that PAE increased the sensitivity of astrocytes to the cytotoxic effects of TNFα when compared to astrocytes prepared from pair-fed a...

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Veröffentlicht in:	Alcohol (Fayetteville, N.Y.) N.Y.), 2000-05, Vol.21 (1), p.63-71
Hauptverfasser:	De Vito, William J, Xhaja, Krisanthi, Stone, Scott
Format:	Artikel
Sprache:	eng
Schlagworte:	Astrocytes Biological and medical sciences Ceramide Drug addictions Embryology: invertebrates and vertebrates. Teratology Fundamental and applied biological sciences. Psychology Medical sciences Prenatal alcohol exposure sphingolipids Teratology. Teratogens TNFα Toxicology tumor necrosis factor-^a
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