Proteolytic Cleavage of Extracellular Secreted α-Synuclein via Matrix Metalloproteinases

Although α-synuclein is the main structural component of the insoluble filaments that form Lewy bodies in Parkinson disease (PD), its physiological function and exact role in neuronal death remain poorly understood. In the present study, we examined the possible functional relationship between α-syn...

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Veröffentlicht in:	The Journal of biological chemistry 2005-07, Vol.280 (26), p.25216-25224
Hauptverfasser:	Sung, Jee Young, Park, Sung Min, Lee, Choong-Hwan, Um, Ji Won, Lee, Hyun Jung, Kim, Jongsun, Oh, Young J., Lee, Seung-Taek, Paik, Seung R., Chung, Kwang Chul
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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