Sucralose: lack of effects on sperm glycolysis and reproduction in the rat

Certain chlorine-substituted sugars with chemical similarities to sucralose have been demonstrated previously to diminish or inhibit sperm glycolysis and fertility in the rat ( Ford and Waites, 1978a). In order to investigate this potential for sucralose, epididymal spermatozoa were recovered from r...

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Veröffentlicht in:	Food and chemical toxicology 2000-01, Vol.38, p.19-29
Hauptverfasser:	Kille, J.W., Ford, W.C.L., McAnulty, P., Tesh, J.M., Ross, F.W., Willoughby, C.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	6-chlorosugars Adenosine Triphosphate - analysis Animals Animals, Newborn artificial sweeteners Body Weight - drug effects Carbon Dioxide - metabolism disaccharides Drinking - drug effects Eating - drug effects Female Fluorometry Glucose - metabolism Glycolysis - drug effects Glycolysis - physiology Litter Size - drug effects Male monosaccharides Random Allocation rat reproduction Rats Rats, Sprague-Dawley Reproduction - drug effects Reproduction - physiology Scintillation Counting Single-Blind Method sperm glycolysis Spermatozoa - drug effects Spermatozoa - metabolism sucralose Sucrose - analogs & derivatives Sucrose - toxicity Sweetening Agents - toxicity
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