μ-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage

The differentiated cells seem to share the ability to induce their own death by the activation of an internally encoded suicide program. When activated, this suicide program initiates a characteristic form of cell death called apoptosis. A central challenge in apoptosis research is understanding the...

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Veröffentlicht in:Brain research 2000-06, Vol.866 (1), p.299-312
Hauptverfasser: Rami, Abdelhaq, Agarwal, Rachna, Botez, Giovannina, Winckler, Jürgen
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Sprache:eng
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