Amyloid Formation Modulates the Biological Activity of a Bacterial Protein

The aggregation of proteins into amyloid fibrils is the hallmark feature of a group of late-onset degenerative diseases including Alzheimer, Parkinson, and prion diseases. We report here that microcin E492, a peptide naturally produced by Klebsiella pneumoniae that kills bacteria by forming pores in...

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Veröffentlicht in:	The Journal of biological chemistry 2005-07, Vol.280 (29), p.26880-26885
Hauptverfasser:	Bieler, Sylvain, Estrada, Lisbell, Lagos, Rosalba, Baeza, Marcelo, Castilla, Joaquín, Soto, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid - biosynthesis Bacterial Proteins - chemistry Bacterial Proteins - physiology Bacteriocins - chemistry Bacteriocins - metabolism Dimerization Evolution, Molecular Kinetics Klebsiella pneumoniae Klebsiella pneumoniae - chemistry Microscopy, Electron
Online-Zugang:	Volltext
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