Transcript imaging of the development of human T helper cells using oligonucleotide arrays

Many pathological processes, including those causing allergies and autoimmune diseases, are associated with the presence of specialized subsets of T helper cells at the site of inflammation. Understanding the genetic program that controls the functional properties of T helper type 1 (Th1) versus T h...

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Veröffentlicht in:	Nature genetics 2000-05, Vol.25 (1), p.96-101
Hauptverfasser:	Rogge, Lars, Bianchi, Elisabetta, Biffi, Mauro, Bono, Elisa, Chang, Sheng-Yung P, Alexander, Heather, Santini, Chris, Ferrari, Giuliana, Sinigaglia, Luigi, Seiler, Monika, Neeb, Martin, Mous, Jan, Sinigaglia, Francesco, Certa, Ulrich
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Agriculture Algorithms Allergies Animal Genetics and Genomics Apoptosis Apoptosis - genetics Apoptosis - immunology Apoptosis Regulatory Proteins Autoimmune diseases Biological and medical sciences Biomedical and Life Sciences Biomedicine Cancer Research Caspase 8 Caspase 9 Caspases - genetics Cell Differentiation - genetics Cell Differentiation - immunology Cell Line Cytokines DNA microarrays Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation - immunology Gene Function Genetics Granzymes Human Genetics Humans Inflammation Inflammatory diseases Kinetics letter Membrane Glycoproteins - biosynthesis Membrane Glycoproteins - genetics Molecular and cellular biology Oligonucleotide Array Sequence Analysis - methods oligonucleotides Perforin Physiological aspects Polymerase Chain Reaction Pore Forming Cytotoxic Proteins Proto-Oncogene Proteins c-bcl-2 - genetics Serine Endopeptidases - genetics T cells T-Lymphocytes, Helper-Inducer - cytology T-Lymphocytes, Helper-Inducer - metabolism Th1 Cells - metabolism Th2 Cells - metabolism TNF-Related Apoptosis-Inducing Ligand Transcription, Genetic - immunology Tumor Necrosis Factor-alpha - genetics Up-Regulation - genetics Up-Regulation - immunology
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