Time course of cardiac inflammation during nitric oxide synthase inhibition in SHR: impact of prior transient ACE inhibition

We have previously demonstrated that angiotensin-converting enzyme (ACE) inhibition with enalapril produces persistent effects that protect against future nitric oxide synthase (NOS) inhibitor (L-arginine methyl ester, L-NAME)-induced cardiac dysfunction and outer wall collagen deposition in spontan...

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Veröffentlicht in:	Hypertension research 2016-01, Vol.39 (1), p.8-18
Hauptverfasser:	Biwer, Lauren A, D'souza, Karen M, Abidali, Ali, Tu, Danni, Siniard, Ashley L, DeBoth, Matthew, Huentelman, Matthew, Hale, Taben M
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Arterial Pressure - drug effects Cell Proliferation - drug effects Chemokine CCL2 - blood Chemokines Cytokines - metabolism Disease Progression Enalapril - pharmacology Enzyme Inhibitors - pharmacology Interleukin-10 - blood Interleukin-6 - blood Macrophages - drug effects Male Myocarditis - chemically induced Myocarditis - pathology Myocarditis - prevention & control NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide Synthase - antagonists & inhibitors Rats Rats, Inbred SHR
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