A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Ca sub(v)1.4 channel activation

Light stimuli produce graded hyperpolarizations of the photoreceptor plasma membrane and an associated decrease in a voltage gated calcium channel conductance that mediates release of glutamate neurotransmitter. The Ca sub(v)1.4 channel is thought to be involved in this process. The CACNA1F gene enc...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2005-05, Vol.102 (21), p.7553-7558
Hauptverfasser: Hemara-Wahanui, Ariana, Berjukow, Stanislav, Hope, Carolyn I, Dearden, Peter K, Wu, Shu-Biao, Wilson-Wheeler, Jane, Sharp, Dianne M, Lundon-Treweek, Patricia, Clover, Gillian M, Hoda, Jean-Charles, Striessnig, Joerg, Marksteiner, Rainer, Hering, Steffen, Maw, Marion A
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Sprache:eng
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