A novel approach to the assessment of vascular endothelial function

A novel approach to the assessment of vascular endothelial function

Impaired endothelial function (EF) is associated with atherogenesis, and its quantitative assessment has prognostic value. Currently, methods based on assessing flow-mediated dilation (FMD) are technically difficult and expensive. We tested a novel way of assessing EF by measuring the time differenc...

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Veröffentlicht in:Journal of physics. Conference series 2011-01, Vol.307 (1), p.12014-7
Hauptverfasser: Sathasivam, S, Phababpha, S, Sengmeuan, P, Detchaporn, P, Siddiqui, Z, Kukongviriyapan, U, Greenwald, S
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Sprache:eng
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Assessments
Dilation
Fingers
Hand (anatomy)
Physics
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container_end_page 7
container_issue 1
container_start_page 12014
container_title Journal of physics. Conference series
container_volume 307
creator Sathasivam, S
Phababpha, S
Sengmeuan, P
Detchaporn, P
Siddiqui, Z
Kukongviriyapan, U
Greenwald, S
description Impaired endothelial function (EF) is associated with atherogenesis, and its quantitative assessment has prognostic value. Currently, methods based on assessing flow-mediated dilation (FMD) are technically difficult and expensive. We tested a novel way of assessing EF by measuring the time difference between pulses arriving at the middle fingers of each hand (f-fΔT), whilst FMD is induced in one arm. We compared f-fΔT with standard methods in healthy and diseased subjects. Our findings suggest that the proposed simple and inexpensive technique gives comparable results and has the potential to qualitatively assess EF in the clinical setting, although further work is required.
doi_str_mv 10.1088/1742-6596/307/1/012014
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subjects Assessments
Dilation
Fingers
Hand (anatomy)
Physics
title A novel approach to the assessment of vascular endothelial function
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