Unfolding Kinetics of Human Telomeric G‑Quadruplexes Studied by NMR Spectroscopy

Characterization of the unfolding kinetics of G-quadruplexes (G4s) is the key to a better understanding of the biological function of G4s and is important for biomedical research and material design. Of interest is that slight variations of human telomeric sequences can form different types of G4 st...

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Veröffentlicht in:	The journal of physical chemistry. B 2014-01, Vol.118 (4), p.931-936
Hauptverfasser:	Li, Ming-Hao, Wang, Zi-Fu, Kuo, Margaret Hsin-Jui, Hsu, Shang-Te Danny, Chang, Ta-Chau
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Correlation Differential scanning calorimetry Exchange G-Quadruplexes Human Humans Kinetics Nuclear magnetic resonance Nuclear Magnetic Resonance, Biomolecular Real time Telomere - chemistry Thermal stability Thermodynamics
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